mutacins

Comparative Antimicrobial Activity of Two New Mutacins

Issue:

Vol 59, issue 6 (2010)

Pages:

602–6

Synopsis:

The comparative in vitro activity of two bacteriocins produced by Streptococcus mutans is presented. Results show that these mutacins are active against pathogens including antibiotic-resistant bacteria. Based on their activity spectra, potential applications are proposed for each bacteriocin.

ABSTRACT

Objectives: To compare the in vitro activity of mutacins D-123.1 and F-59.1 against different bacteria including antibiotic-resistant strains, in order to evaluate their application potential.

Design and Methods: The antibacterial activity spectrum of purified F-59.1 and the MIC and MBC of F-59.1 and D-123.1 against target bacteria were determined.

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