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Evaluation of Alanine Aminotransferase (ALT) and Gamma-glutamyl Transferase (GGT) in Patients with Type 2 Diabetes Mellitus (T2DM) at the Diabetic Clinic, Guyana

High prevalence of elevated ALT and GGT in type 2 diabetic patients showed a strong association to metformin and ethnicity in particular those of Indian decent. Family history showed a greater risk factor of high ALT followed by current illness.


Objective: To determine the prevalence of alanine aminotransferase (ALT) and gamma-glutamyl transferase (GGT) abnormalities and contributing factors in adult patients with Type 2 diabetes mellitus at the diabetic clinic of public hospital, Guyana.

12 Aug, 2016
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e-Published: 12 Aug, 2016

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Proteins and Liver Function Changes in Rats Following Cumulative Total Body Irradiations

Cumulative total body irradiation caused subtle but significant changes in liver function enzymes and proteins which may be due to non-specific stress reactions; as such they are important markers in radiation induced injury diagnosis.


Objective: Total body irradiation (TBI) is a choice therapy for the management of some malignancies; it is also a major cause of oxidative stress. The aim of this research is to sequentially document the effect of total body radiation on body function utilizing the sequential changes in liver function enzymes and proteins in rats.

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e-Published: 21 Jan, 2013
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