CR Nwokocha

The direct interaction between the parasitized erythrocytes and vascular endothelial cells altered contractile responses in vascular rings. The regulation of vascular tone by various vasoactive agents following exposure to malaria parasites might be altered in a vessel-specific manner.

ABSTRACT

Objective: Adherence of erythrocytes infected with Plasmodium falciparum (P falciparum) to microvascular endothelial cells (sequestration) is considered to play an important role in parasite virulence and pathogenesis. In this study, we have examined the possibility that there is altered vascular reactivity due to the direct interaction between the parasitized erythrocytes and vascular endothelial cells and that it could be tissue specific.

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e-Published: 31 Jan, 2014

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Altered Vascular Reactivity Induced By Malaria Parasites

Issue:

Vol 60, issue 1 (2011)

Pages:

13–8

Synopsis:

The direct interaction between the parasitized erythrocytes and vascular endothelial cells altered contractile responses in aortic rings of rats.

Objective: In this study, we have examined the possibility that there is altered vascular reactivity due to the direct interaction between parasitized erythrocytes and vascular endothelial cells.

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e-Published: 17 Oct, 2013

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Malaria: Morbidity, Mortality and its Associated Complications

Issue:

Vol 60, issue 1 (2011)

Pages:

1–2

INTRODUCTION

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editorial_dr_ibanga.qxd_.pdf

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e-Published: 17 Oct, 2013

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Serum Lipids, Proteins and Electrolyte Profiles in Rats Following Total Body Irradiation

Issue:

Vol 61, issue 2 (2012)

Pages:

117–21

Synopsis:

Cumulative total body irradiation caused subtle but significant changes in serum lipids, electrolytes and protein which may be due to non-specific stress reactions. As such, they are important markers in the diagnosis of radiation induced injury.

ABSTRACT

Objective: Serum lipid and electrolyte imbalances are common in critically ill patients undergoing radiation therapy. Although multiple disease states and medication may be responsible for the development of these disorders, the aim of this research is to sequentially document the effect of total body radiation on body function utilizing the sequential changes in the serum lipids, electrolytes and protein in rats.

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e-Published: 19 Aug, 2013

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Effect of Gongronema latifolium Ethanol Leaf Extract on Gastric Acid Secretion and Cytoprotection in Streptozotocin-induced Diabetic Rats

Issue:

Vol 61, Issue 9 (2012)

DOI:

10.7727/wimj.2011.040

Pages:

853–60

Synopsis:

Gongronema latifolium leaves have been used to manage diabetic symptoms and alleviate dyspepsia. The leaves of Gongronema latifolium increase gastric acid output and prevent gastric ulcer in diabetic rats.

ABSTRACT

Objectives: Gongronema latifolium leaves have been used in folklore medicine to manage diabetes mellitus and alleviate dyspepsia. This study aimed to provide a pharmacological basis to the medicinal use of Gongronema latifolium as an antidiabetic and antiulcerogenic agent in diabetes mellitus.

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e-Published: 24 Jun, 2013

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Protein and Liver Function Changes Following Body Irradiation: 'A Research Needs' for Further Exploration in Present Day Man-made Environmental Changes

Issue:

Vol 61, Issue 8 (2012)

DOI:

10.7727/wimj.2013.037

Pages:

771–2

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Editorial

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total body irradiation

Irradiation injuries

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TT Marchie

CR Nwokocha

e-Published: 08 Apr, 2013

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Effect of Gongronema latifolium Ethanol Leaf Extract on Gastric Acid Secretion and Cytoprotection in Streptozotocin-induced Diabetic Rats

DOI:

10.7727/wimj.2011.040

ABSTRACT

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e-Published: 20 Feb, 2013

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Pre-published Manuscript

This manuscript has been assigned to a volume and issue but has not yet been published. It is either being edited, typeset or is in the proof stage of publication.
In the pre-published stage, this manuscript may contain statements, opinions, and information that have errors in facts, figures, or interpretation. Any final changes in this manuscript will be made at the time of publication and will be reflected in the final electronic version of the issue. The editors and authors and their respective employees are not responsible or liable for the use of any such inaccurate or misleading data, opinion or information contained in the articles in this section.

Proteins and Liver Function Changes in Rats Following Cumulative Total Body Irradiations

Issue:

Vol 61, Issue 8 (2012)

DOI:

10.7727/wimj.2011.174

Pages:

773–7

Synopsis:

Cumulative total body irradiation caused subtle but significant changes in liver function enzymes and proteins which may be due to non-specific stress reactions; as such they are important markers in radiation induced injury diagnosis.

ABSTRACT

Objective: Total body irradiation (TBI) is a choice therapy for the management of some malignancies; it is also a major cause of oxidative stress. The aim of this research is to sequentially document the effect of total body radiation on body function utilizing the sequential changes in liver function enzymes and proteins in rats.

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