Cleidocranial dysplasia (CCD) is a rare congenital skeletal disorder that affects the intramembranose ossification bones and teeth and shows an autosomal inheritance pattern. The disorder is characterized by hypoplasia or aplasia of the clavicles, delayed closure of the fontanelles, supernumerary teeth, short stature. The responsible gene for the pathogenesis of CCD is RUNX2 (1-4).
24 Mar, 2016
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