Beta-thalassaemia major patients require monthly blood transfusions. Studies on the oxidant-antioxidant indices in patients on desferrioxamine-chelation or without chelation indicate that desferrioxamine chelation does not normalize ferritin level but attenuates oxidative damage and improves total antioxidant level in these patients.
M-P Nyi Nyi, TN Gibson, B Hanchard, N Waugh, D McNaughton
The incidence of prostate cancer in Kingston and St Andrew, Jamaica, is lower than that in black populations in developed Western countries, but has been increasing since 1983, and is likely to continue to increase over the next several years.
O Ojurongbe, AF Fagbenro-Beyioku, OA Adeyeba, JF Kun
Influence of genetic diversity of merozoite surface
protein (MSP2) of Plasmodium falciparum on age and
gender was investigated in children presenting with
uncomplicated malaria at a provincial health facility
in Nigeria. No significant correlation was observed
between the MSP2 loci and parasite density on age or
The study found that pigment production was significantly
associated with multi-drug resistance, presence
of virulence-associated genes, and expression of some
important virulence factors. The authors conclude that
since pigment production is easy to determine, this
might be a good starting point to identify the virulence
status of an isolate.
SI Smith, KS Oyedeji, HA Goodluck, MA Fowora, E Anomneze, OA Lesi
The Helicobacter pylori Stool Antigen could be appropriate for the
diagnosis and monitoring of Helicobacter pylori in Nigeria due to its
relatively affordable cost and availability, unlike its counterpart and
gold standard the urea breath test.
This study has investigated the organization of vagal brainstem nuclei
in the agouti and has shown organisation pattern similar to those of
other commonly used laboratory animals. The larger size of this
species makes it a suitable alternative experimental animal.
DS Arathy, G Vanpee, G Belot, V Mathew, C DeAllie, R Sharma
The antimicrobial resistance profile of Escherichia coli isolated from
450 commercial chicken eggs in Grenada was studied. The data indicate that chicken eggs used in Grenada can
harbour drug resistant E coli.
K Tomkins, J Raynor, L Rothwell, J DeSilva, C Wilson
Hospital antibiotic stewardship, combined with an
effective infection prevention and control programme,
can lead to better outcomes in the management of
patients with Clostridium difficile-associated diarrhoea.
BF Morrison, K Coard, G Strachan, R Miller, W Aiken, R Mayhew
This article represents an eight-year retrospective review
of radical prostatectomies performed at the University
Hospital of the West Indies. Oncological outcomes
and morbidity are compared to large- volume
In this study, 18 patients who have had a perilunate
injury with dislocation or fracture were evaluated.
When the pathomechanics was estimated based on the
Mayfield’s criteria, 17 patients were classified into
state 3. However, only one case was extremely unusual
and should be classified as the subtype of state 2.
Posterior ankle impingement has not been described in
cricket but is associated with ballet and soccer. An
increase in this condition with development of os
trigonum is being seen among fast bowlers in cricket.
Treatment options are affected by bowling loads
This study reports the long-term surgical outcomes of
elderly patients with humeral neck fractures who
underwent treatment using the modified Hackethal
bundle nailing method on the basis of an approximately
10-year follow-up study. This method is simple and less
R Balkaran, R Naidu, S Teelucksingh, T Seemungal, L Pinto Pereira, E Prayman, A Bissoon
A preliminary report on the dental evaluation of
diabetic patients suggests that periodontal disease may
be quite prevalent in diabetic patients in Trinidad.
Collaborative patient care between medical and dental
practitioners should form part of the routine management
of diabetic patients.
O James, JNA Ajuluchukwu, AL Ladeinde, WL Adeyemo, OM Gbotolorun, MO Ogunlewe
The haemodynamic changes induced by injecting 2%
lignocaine with adrenaline in patients with controlled
hypertension during tooth extraction is within normal
range and is not different from that induced by 2%
lignocaine without adrenaline.