YY1, a critical regulator in prostate cancer, is predicted to be a direct target of miR-146a and binds to promoter region of miR-146a which demonstrates that YY1-miR-146a-YY1 regulatory circuitry may contribute to prostate cancer and serve as a future intervention target.
Autophagy, partly through activation of haem oxygenase-1 (HO-1) pathway, may protect from ventilator-induced lung injury, which might be a new potential therapeutic target for ventilator-induced lung injury.