X Zhang

De novo CD5-positive Diffuse Large B-cell Lymphoma Primarily Presenting as Spinal Cord Compression: A Case Report

Issue:

Vol 2, Issue 2 (2015)

DOI:

10.7727/wimjopen.2015.009

Pages:

106–8

ABSTRACT

De novo CD5-positive (CD5+) diffuse large B-cell lymphoma (DLBCL) is a highly aggressive subtype of DLBCL with a high incidence of misdiagnosis when spinal cord compression is the initial symptom. We report a case of a 45-year old man with de novo CD5+ DLBCL primarily presenting as spinal cord compression. Unfortunately, this patient was resistant to rituximab-based therapy, which indicated a poor prognosis.

Received:

January 21, 2015

Accepted:

February 5, 2015

Published:

May 29, 2015

PDF Attachment:

Ren et al--CD5-DLBCL Presenting as Spinal Cord Compression.pdf

Journal Sections:

Case Reports

Keywords:

lymphoma

spinal cord compression

CD5-positive diffuse large B-cell

Journal Authors:

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Antineutrophil Cytoplasmic Antibody-negative Pauci-immune Crescentic Glomerulonephritis and Mantle-cell Lymphoma: A Case Report and Review of the Literature

Issue:

Vol 1, Issue 3 (2014)

DOI:

10.7727/wimjopen.2014.198

Pages:

114–6

Synopsis:

We report on a rare case of antineutrophil cytoplasmic antibody (ANCA)-negative pauci-immune crescentic glomerulonephritis (GN) probably due to mantle-cell lymphoma (MCL). Chemotherapy may improve the outcome. The pathophysiologic relationship between ANCA-negative pauci-immune crescentic GN and MCL should be investigated further.

ABSTRACT

Received:

August 26, 2014

Accepted:

September 8, 2014

Published:

December 22, 2014

PDF Attachment:

Wang et al--ANCA-negative Crescentic Glomerulonephritis and Mantle-cell Lymphoma.pdf

Journal Sections:

Case Reports

Keywords:

ANCA

antineutrophil cytoplasmic antibody

mantle-cell lymphoma

pauci-immune crescentic glomerulonephritis

Journal Authors:

Read more about Antineutrophil Cytoplasmic Antibody-negative Pauci-immune Crescentic Glomerulonephritis and Mantle-cell Lymphoma: A Case Report and Review of the Literature

YY1-miR-146a-YY1 Regulatory Circuitry: A Potential Mechanism of Prostate Cancer Formation and Progression

Issue:

Vol 1, Issue 2 (2014)

DOI:

10.7727/wimjopen.2013.314

Synopsis:

YY1, a critical regulator in prostate cancer, is predicted to be a direct target of miR-146a and binds to promoter region of miR-146a which demonstrates that YY1-miR-146a-YY1 regulatory circuitry may contribute to prostate cancer and serve as a future intervention target.

ABSTRACT

Received:

November 15, 2013

Accepted:

January 20, 2014

PDF Attachment:

Chen et al--YY1-miR-146-YYI regulatory cicuitry.pdf

Journal Sections:

Original Articles

Keywords:

MicroRNA-146a (miR-146a)

prostate cancer