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Treatment of Hepatitis C According to Regional Treatment Guidelines

DOI: 
10.7727/wimj.2016.497

ABSTRACT

Objective: Was present a general overview of the current treatments for HCV infection in adults.

Methods: A review study was conducted, Databases such as PubMed, MEDLINE and Scopus were used as information sources to identify and analyze the current information about the treatment for HCV infection in adults

Results: To define a treatment with the best likelihood of success, it is important to identify in each patient, their response predictors such as genotype and viral load as vital determinants. In addition, to age, male gender, prolonged infection, cirrhosis, hepatic fibrosis, elevated plasma ferritin, obesity, insulin resistance, African American and Hispanic ancestry and co-infection with HIV). Recently, it has been approved that the other drugs with direct antiviral activity (DAAs), like the protease inhibitors (Boceprevir and Telaprevir), inhibitors of the polymerase NS5B (deleobuvir and setrobuvir), inhibitors of replication complex NS5A, include daclatasvir, ledipasvir and cyclophilin inhibitors were introduced into clinical practice but this use is subject to the purchasing power of health institutions

Conclusion: To define a treatment with the best likelihood of success, it is important to identify in each patient, their response predictors such as genotype and viral load as vital determinants.

Accepted: 
11 Jan, 2017
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e-Published: 25 Jan, 2017

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