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hepatitis C

Treatment of Hepatitis C According to Regional Treatment Guidelines

DOI: 
10.7727/wimj.2016.497
Synopsis: 
The interferon-free regimens DAAs-based treatments have demonstrated the potential to cure HCV infection in adults with very high percentages and with good tolerability.

ABSTRACT

Objective: Was present a general overview of the current treatments for HCV infection in adults.

Methods: A review study was conducted, Databases such as PubMed, MEDLINE and Scopus were used as information sources to identify and analyze the current information about the treatment for HCV infection in adults

Accepted: 
11 Jan, 2017
PDF Attachment: 
Journal Sections: 
e-Published: 25 Jan, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Association between Mannose-Binding Lectin 2 Gene Polymorphism and Liver Fibrosis in Patients with Chronic Viral Hepatitis

DOI: 
10.7727/wimj.2016.155
Synopsis: 
MBL2 Gene Polymorphism were investigated in patients with viral Hepatitis B and C. No significant differences in allele frequencies for any polymorphism were observed between patients and controls.

ABSTRACT

Objective: Mannose-Binding Lectin (MBL) has become a popular molecule in investigations on basic and clinical Gastroenterology and contributed to new approaches to the understanding of infectious and immune diseases associated with intestine and liver. The aim of the present study was to investigate the association between codon 54 polymorphisms in MBL2 gene coding MBL and predisposition to fibrosis in patients with viral Hepatitis B and C.

Accepted: 
25 May, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 14 Jul, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Expectations of Treatment of Hepatitis C in Children

DOI: 
10.7727/wimj.2016.153
Synopsis: 
The study aimed at presenting a general overview of the current treatments for HCV infection in children. In children the most commonly used drugs are pegylated alpha interferon in combination with ribavirin only Boceprevir was tested and not approved for use in children. Safety and efficacy of new drugs in children need further investigation.

ABSTRACT

Background: HCV infection in children differs from infection in adult through transmission paths, spontaneous viral clearance rate, and fibrosis progression duration of chronic infection. It is estimated that the rate of children with chronic hepatitis C will develop cirrhosis is less than 2%, however there are reports of children requiring liver transplantation. 

Accepted: 
25 May, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 14 Jul, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Partial Protection from Metabolic Syndrome in Chronic Hepatitis C Elderly Subjects Due to Lower Triglyceride Level

Issue: 
DOI: 
10.7727/wimj.2014.123
Pages: 
116–22
Synopsis: 
Chronic hepatitis C is a protective factor against having metabolic syndrome and this effect might be due to lower triglyceride level in the elderly. Further studies are warranted for the underlying mechanisms.

ABSTRACT

Background: In Taiwan, subjects over 65 years old have higher prevalence of hepatitis C. Among these patients, around 50% have non-alcoholic fatty liver disease (NAFLD). Since cardiovascular diseases and diabetes are main causes of death in this age group, in this cross-sectional study, we tried to evaluate the effects of NAFLD and hepatitis C on the risk of metabolic syndrome (MetS).

Accepted: 
12 Aug, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 11 May, 2015
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