Close Menu

Cannabinoids and Cannabis Based Medicines in the Treatment of Chronic Pain: A Review

Journal Authors: 
DOI: 
10.7727/wimj.2016.513

ABSTRACT

Cannabinoids isolated from cannabis spp. have been the subject of much research over at least three decades. Extensive research has been conducted on the mode of action of this group of compounds which elicits a variety of therapeutic activity. Research has revealed that phytocannabinoids have similar activity as endocannabinoids {ElSohly, 2007 #10}and can act as ligands in the endocannabinoid system. The endocannabinoid system is a neuromodulatory system that regulates some important bodily functions. With the existing preclinical and clinical trials and the activity of cannabis derived analgesics, cannabinoids shows great potential in curtailing the concerns of traditional pain modulators. This review article highlights research on cannabinoids as an analgesic in the management of several pain states such as neuropathy, migraine, arthritis, and sickle cell disease.

Accepted: 
11 Jan, 2017
PDF Attachment: 
e-Published: 25 Jan, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Top of Page