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Cannabis

Old Herb, ‘New’ Purpose: A Preliminary Analysis of Marijuana as a Medicine in Barbados

Issue: 
DOI: 
10.7727/wimj.2018.136
Pages: 
53-8
Synopsis: 
This article analysed the potential of Cannabis sativa as a medicine in Barbados.

ABSTRACT

Accepted: 
03 Jan, 2019
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 25 Mar, 2019

Dosage and Conditioning Period Determine Reward or Aversion to Cannabis-induced Conditioned Place Preference in Sprague-Dawley Rats

Issue: 
DOI: 
10.7727/wimj.2017.185
Pages: 
523-8
Synopsis: 
The study demonstrated that a shortened conditioning period of 18 minutes in the conditioned place preference paradigm could induce significant delta-9-tetrahydrocannabinol (∆9-THC) reward at low doses, supporting the addictive potential of the psychoactive agent of marijuana. This is the first report of significant reward at a dose of 0.05 mg/kg of ∆9-THC in an animal model of addiction.

ABSTRACT

Objective: To assess the addictive potential of cannabis by investigating the motivational responses to low doses of delta-9-tetrahydrocannabinol (Δ9-THC) and a marijuana tea extract (MTE), and to determine if the length of the conditioning period in the conditioned place preference (CPP) paradigm influences reward or aversion to these cannabinoid preparations.

Accepted: 
23 Oct, 2017
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 19 Dec, 2017

Cannabinoid Hyperemesis Syndrome in an East Indian: The Case for Genetic Susceptibility

Issue: 
DOI: 
10.7727/wimj.2017.229
Pages: 
581-2

The Editor,

Sir,

Following the first description of Cannabinoid Hyperemesis Syndrome (CHS) in 2004, there have been hundreds of cases reported, up to recently. One of the largest series was at the Mayo Clinic (a non-profit organization in the United States of America) where five African-American patients, three Hispanics and 12 patients of ‘Other’ ethnicities were noted in a series of 98 cases of predominantly Caucasian patients (1, 2).

Revised: 
27 Oct, 2017
Accepted: 
27 Oct, 2017
PDF Attachment: 
Journal Sections: 
e-Published: 19 Dec, 2017

Cannabis Use among Secondary School Students in Jamaica: Factors Associated with Age of Initiation

Issue: 
DOI: 
10.7727/wimj.2017.214
Pages: 
546-52
Synopsis: 
The aim of the study was to determine whether perception of risk and accessibility of cannabis predicted the age of initiation of cannabis among secondary school students in Jamaica. Whereas there was a significant inverse association between grade level in school and age of initiation, perceptions of access did not predict the age of initiation of cannabis.

ABSTRACT

Accepted: 
23 Oct, 2017
PDF Attachment: 
Journal Sections: 
e-Published: 26 Oct, 2017

Dosage and Conditioning Period Determine Reward or Aversion to Cannabis-induced Conditioned Place Preference in Sprague-Dawley Rats

DOI: 
10.7727/wimj.2017.185
Synopsis: 
The study demonstrated that a shortened conditioning period of 18 minutes in the conditioned place preference (CPP) paradigm can induce significant ∆9-THC reward at low doses, supporting the addictive potential of the psychoactive agent of marijuana. This is the first report of significant reward at a dose of 0.05 mg/kg ∆9-THC in an animal model of addiction.

  ABSTRACT                                                                                                                                     

Accepted: 
23 Oct, 2017
Journal Sections: 
Journal Authors: 
e-Published: 26 Oct, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

From Cannabis to the Endocannabinoid System: Refocussing Attention on Potential Clinical Benefits

Issue: 
Pages: 
264–70
Synopsis: 
In this review, we seek to highlight advances made over the last forty years in the understanding of the mechanisms responsible for the effects of cannabis on the human body and how these can potentially be utilized in clinical practice.

ABSTRACT

PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 21 Aug, 2013

Cannabinoids and Cannabis Based Medicines in the Treatment of Chronic Pain: A Review

DOI: 
10.7727/wimj.2016.513
Synopsis: 
Anecdotal and traditional use has long proclaimed the use of cannabis in the management of a number of pain conditions. The article outlines the use of cannabinoids and cannabis based medicines in the treatment of chronic pain.

ABSTRACT

Accepted: 
11 Jan, 2017
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 25 Jan, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

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