Synopsis:
The anti-inflammatory effects of Cassia alata leaf extract were investigated on complete Freund’s adjuvant induced arthritic rats. The extract from the leaves was able to significantly reduce the swelling observed in the knee joint. It was also able to effectively protect the articular cartilage from degradation as well as limit the number of differential leukocytes entering the synovial cavity during inflammation. Cassia alata possesses potent anti-inflammatory effects and should undergo further investigations of these properties.