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Six-shogaol inhibits Production of Tumour Necrosis Factor Alpha, Interleukin-1 beta and Nitric Oxide from Lipopolysaccharide-stimulated RAW 264.7 Macrophages

Six-shogaol is a major constituent of the rhizome from the ginger plant. In this study, evidence that 6-shogaol significantly inhibited production of pro-inflammatory cytokines TNF-alpha, IL-1 beta and nitric oxide from lipopolysaccharide stimulated RAW 264.7 macrophages was obtained. Such inhibition might explain the anti-inflammatory mechanisms and the therapeutic potential of this ginger compound.


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e-Published: 19 Sep, 2013
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