F Ekici

Brain Magnetic Resonance Imaging Findings and Distribution of the Findings According to the Age Groups in Childhood Epilepsies

Issue:

Vol 71, Issue 1: 2024

DOI:

10.7727/wimj.2017.175

Pages:

63-8

Synopsis:

This study showed that the most common pathology that caused epilepsy in children was the indication of parenchymal damage. Another common pathology is hippocampal sclerosis and cortical developmental abnormalities. MRI is a non-invasive imaging modality that that does not involve any ionizing radiation and can be used to identify pathologies that lead to epileptic attacks in childhood.

ABSTRACT

Objective: To retrospectively analyse the magnetic resonance imaging (MRI) observations and the distribution of etiological factors according to age groups in cases with MRI examinations for an epilepsy diagnosis.

Methods: The brain MRI of 606 cases from the 0–17 years age group were analysed retrospectively, and the findings were evaluated according to the age group.

Received:

11 Sep, 2017

Accepted:

12 Dec, 2017

Published:

30 Mar, 2024

PDF Attachment:

wimj-iss1-2024_63_68.pdf

Journal Sections:

Original Articles

Keywords:

children

epilepsy

magnetic resonance imaging.

Journal Authors:

e-Published: 18 Jan, 2018

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Effects of Endothelin-A Receptor Antagonist BQ-123 on Plasma Leptin Levels Streptozotocin Induced Diabetic Rats

Issue:

Vol 70, Issue 1: 2023

DOI:

10.7727/wimj.2016.106

Pages:

61-8

Synopsis:

Leptin and endothelin (ET), as important endogenous factors, interact with each other which may contribute to a better understanding of their role in diabetic pathogenesis. We aimed to evaluate the relationship between leptin and ET by investigating the influence of BQ-123, an ET-A receptor (ETAR) antagonist, on leptin levels in rats with diabetes induced by streptozotocin (STZ). In this study, 24 male, Wistar-albino rats were divided into three groups: Control, STZ, STZ + BQ-123 groups. BQ-123 relatively reduced oxidative stress and leptin levels. ETAR antagonist BQ-123 has positive impacts, depending on the dosage in the diabetic rats.

ABSTRACT

Objective: Leptin and endothelin (ET) as important endogenous factors interacting with each other which may contribute to a better understanding of their role in diabetic pathogenesis. We aimed to evaluate the relationship between leptin and ET by investigating the influence of BQ-123, an ET-A receptor (ETAR) antagonist, on leptin levels in rats with diabetes induced by streptozotocin (STZ).

Received:

10 Mar, 2016

Accepted:

25 May, 2016

Published:

29 Nov, 2023

PDF Attachment:

wimj-iss1-2023_61_68.pdf

Journal Sections:

Original Articles

Keywords:

BQ-123