This is the first report of the University of the West Indies (UWI) breast cancer immunohistochemistry (IHC) receptor database in which we present the results of tests performed during the six year period following its establishment in 2002, and investigate the associations between receptor profile and patient age, tumour grade and stage.

In this study, high prevalence of elevated Alanine Aminotransferase (ALT) and Gamma-glutamyl Transferase (GGT) in type 2 diabetic patients showed a strong association with metformin use and ethnicity, particular those of Indian decent. Family history showed a greater of high ALT followed by current illness.

This study showed that the prevalence of Gastroesophageal Reflux Disease (GERD) symptoms in Jamaican subjects within the previous year was 71.1%. Weekly symptoms were present in 18.6% with moderate or greater severity in 11.7%. The most common and bothersome symptom was heartburn. Nocturnal symptoms occurred in 17.8%. In persons with GERD symptoms, 24.2% (P= 0.000) saw a doctor and 38.6% took medication (p<0.0001).

In this study, we aimed to review the surgical outcomes of primary mediastinal cysts and to determine the differences among various histopathological types. We retrospectively analyzed the medical records of 41 patients with primary mediastinal cysts who underwent surgical excision. We found that despite advanced non-invasive diagnostic techniques, the definitive diagnosis of primary mediastinal cysts can only be made by interventional techniques. Surgery often provides curative therapy with low morbidity and mortality.

In this study, an additional locking plate and the derived Poller screw technique effectively improved local rotation instability and is an effective and simple treatment method for femoral non-union after intramedullary nailing.

Leptin and endothelin (ET), as important endogenous factors, interact with each other which may contribute to a better understanding of their role in diabetic pathogenesis. We aimed to evaluate the relationship between leptin and ET by investigating the influence of BQ-123, an ET-A receptor (ETAR) antagonist, on leptin levels in rats with diabetes induced by streptozotocin (STZ). In this study, 24 male, Wistar-albino rats were divided into three groups: Control, STZ, STZ + BQ-123 groups. BQ-123 relatively reduced oxidative stress and leptin levels. ETAR antagonist BQ-123 has positive impacts, depending on the dosage in the diabetic rats.