G Ozbilim

Identification of Epidermal Growth Factor Receptor Mutations and Anaplastic Lymphoma Kinase Gene Rearrangement in Lung Adenocarcinomas

DOI:

10.7727/wimj.2018.065

Synopsis:

The identification of molecular alterations has an important therapeutic implication in patients with lung adenocarcinomas. In this study, we presented our experience with the identification of EGFR and ALK mutations using tissue specimens of primary and metastatic lung adenocarcinomas.

ABSTRACT

Objective: The identification of molecular alterations has an important therapeutic implication in lung adenocarcinoma patients. Herein, we presented our experience with the identification of epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase(ALK) mutations in primary and metastatic lung adenocarcinomas.

Received:

16 Apr, 2018

Accepted:

08 May, 2018

PDF Attachment:

ozbudak_et_al_-_identification_of_epidermal_growth.pdf

Journal Sections:

Original Articles

Keywords:

Anaplastic lymphoma kinase mutation

epidermal growth factor receptor mutation

Journal Authors:

e-Published: 15 Feb, 2019

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Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Effect of a Cholesterol Rich Diet, Recurrent Infection and Possible Treatment Modalities on the Pulmonary Vascular System: An Experimental Study

Issue:

Vol 60, issue 2 (2011)

Pages:

132–6

Synopsis:

The study was designed to investigate the effects of infection and/or cholesterol rich diet combined with therapeutic and preventative agents such as antibiotic, anti-inflammatory agent and red wine on the pulmonary vascular system.

ABSTRACT

Objective: Infection may lead to inflammation, atherosclerosis and thrombotic vascular events. The atherosclerotic effect of hypercholesterolaemia on the vascular system is well-known. However, limited studies were done on the therapeutic and preventative agents. The aim of this study was to investigate the effects of infection and cholesterol rich diet combined with an antibiotic, anti-inflammatory agent and red wine on the pulmonary vascular system.

PDF Attachment:

dr_ozbudak_wimj.qxd_.pdf

Journal Sections:

Keywords:

Journal Authors: