Resveratrol might ameliorate diabetes-induced renal damage though mediating the balance of Th17/Treg-related cytokines and inhibiting the expression TGF-β1 and collagen IV.
ABSTRACT
Objectives: This study aimed at detecting the protective effects of resveratrol on diabetes-induced renal damage and on the expression of transforming growth factor-beta 1 (TGF-β1), collagen IV and Th17/Treg-related cytokines in streptozotocin-induced diabetic rats.