Zhou Wenbin

Resveratrol Ameliorates Diabetes-induced Renal Damage through Regulating the Expression of TGF-B1, Collagen IV and Th17/Treg-Related Cytokines in Rats

Issue:

Vol 63, Issue 1: Jan (2014)

DOI:

10.7727/wimj.2014.008

Pages:

20–5

Synopsis:

Resveratrol might ameliorate diabetes-induced renal damage though mediating the balance of Th17/Treg-related cytokines and inhibiting the expression TGF-β1 and collagen IV.

ABSTRACT

Objectives: This study aimed at detecting the protective effects of resveratrol on diabetes-induced renal damage and on the expression of transforming growth factor-beta 1 (TGF-β1), collagen IV and Th17/Treg-related cytokines in streptozotocin-induced diabetic rats.

Received:

31 Jan, 2014

Accepted:

12 Feb, 2014

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