Combining the use of diffusion tensor imaging and susceptibility weighted imaging can provide a sensitive method for differentiating between MPTP-induced rhesus monkey model of Parkinson’s disease and wild-type controls.
ABSTRACT
Objective: The aim of this study was to evaluate whether combining diffusion tensor magnetic resonance imaging (DTI) and susceptibility weighted imaging (SWI) techniques would provide a sensitive method for differentiating between 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced rhesus monkey model of Parkinson’s disease (PD) and wild-type controls.