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K Giaslakiotis

Does Helicobacter Pylori Identification in the Mucosa of the Gallbladder Correlate to Cholesterol Gallstone Formation?

Using both standard histology and polymerase chain reaction, H pylori was detectable in a low frequency in the mucosa of the gallbladder and no statistical differences were found between patients with cholesterol gallstones and patients without cholelithiasis. Thus, H pylori does not seem to act as a lithogenic component for cholesterol gallstone formation.


Objective: Helicobacter pylori (H pylori) represents a potential initiator of cholesterol crystallization and it has been proposed that it is related to gallstone formation. In this study, any possible association between the H pylori identification in the mucosa of gallbladder and cholesterol gallstone formation was evaluated.

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e-Published: 20 Sep, 2013
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