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Interferon-α

The Effect of Combining Interferon-a and Gefitinib in Human Colon Cancer Cell Lines

Issue: 
Pages: 
107–13
Synopsis: 
Li Yang, Fang Wang, Fang He, LiYa HUANG Interferon-α promotes the antiproliferative effect of gefitinib on human colon cancer cell lines SW-480 and LOVO.

ABSTRACT

Background and Aims: Interferon-α (IFN-α) treatment is associated with up-regulation of epidermal growth factor receptor (EGFR) expression and marked growth inhibition of colon cancer cell lines. We aimed to determine the effect of combining IFN-α and gefitinib in the growth of human colon cancer cell lines.

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e-Published: 17 Oct, 2013
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