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LC-MS

A Rapid and Sensitive LC-MS Method for the Estimation of Tolterodine Tartrate in Human Plasma

DOI: 
10.7727/wimj.2015.274
Synopsis: 
A selective and sensitive high performance liquid chromatography-electrospray ionization mass spectrometry method has been developed for the determination of tolterodine tartrate in human plasma. The validated LC–ESI–MS method has been used successfully to study tolterodine tartrate pharmacokinetic, bioavailability and bioequivalence in 12 healthy male volunteers.

ABSTRACT

Accepted: 
24 Aug, 2015
Journal Sections: 
Journal Authors: 
e-Published: 06 Nov, 2015

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Manuscripts that are “Published at Acceptance” have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear prior to being copy edited or formatted in the style guide of this Journal. The contents of the manuscript may change before it is published in its final form. While accepted manuscripts are not yet assigned a volume, issue, or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. Manuscripts in this section will be removed once they have been assigned to a volume and issue, but will still retain the DOI and date of e-publication.

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