Close Menu

microalbumin measurement

Diagnostic Accuracy of Spot and Timed Measurements of Urinary Albumin Concentration to Determine Microalbuminuria in Sickle Cell Disease

Issue: 
DOI: 
10.7727/wimj.2012.323
Synopsis: 
We report that in sickle cell disease, both spot and two-hour timed urine collections for measurements of albumin concentration or albumin:creatinine ratios are good proxy measures of total 24-hour albumin excretion. These much simpler, and likely more cost-effective, methods can be applied in clinical practice with confidence.

ABSTRACT

Objective: Whereas measurement of albumin:creatinine ratio (ACR) in spot urine samples is indicated for determining microalbuminuria, its performance or that of urinary albumin excretion rate (UAER) in predicting microalbuminuria in sickle cell disease (SCD) is unclear. We therefore tested the diagnostic performance of these measures in spot and timed urine samples in predicting a UAER in 24-hour samples.

Revised: 
26 Jun, 2013
Accepted: 
04 Sep, 2013
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 29 Nov, 2013

Pre-published Manuscript

This manuscript has been assigned to a volume and issue but has not yet been published. It is either being edited, typeset or is in the proof stage of publication.
In the pre-published stage, this manuscript may contain statements, opinions, and information that have errors in facts, figures, or interpretation. Any final changes in this manuscript will be made at the time of publication and will be reflected in the final electronic version of the issue. The editors and authors and their respective employees are not responsible or liable for the use of any such inaccurate or misleading data, opinion or information contained in the articles in this section.

Subscribe to RSS - microalbumin measurement
Top of Page