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Multiple-drug resistance

Cytokine-induced Killer Cells Co-cultured with Dendritic Cell Benefit for the Treatment of MCF-7/ADR-Mammary Cancer with Multi-drug Resistance

After cytokine-induced killer cells (CIK) were co-cultured with dendritic cells (DC) loaded with multi-drug resistance tumor antigen, the higher antitumour immune response was evaluated to multi-drug resistance tumor expressed as the same tumour antigen. This provided the effective, clinical treatment for the multi-drug resistance tumour.


Cytokine-induced killer cells (CIK) are capable of lysing tumor cell and recognizing these cells in a non-MHC restricted fashion. After they were co-cultured with Dendritic cells (DC) loaded multidrug resistance tumor antigen, do they have the higher antitumor effect to the same multidrug resistance tumor?

11 Sep, 2015
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e-Published: 03 Nov, 2015


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