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Multiple-drug resistance

Cytokine-induced Killer Cells Co-cultured with Dendritic Cell Benefit for the Treatment of MCF-7/ADR-Mammary Cancer with Multi-drug Resistance

DOI: 
10.7727/wimj.2015.474
Synopsis: 
After cytokine-induced killer cells (CIK) were co-cultured with dendritic cells (DC) loaded with multi-drug resistance tumor antigen, the higher antitumour immune response was evaluated to multi-drug resistance tumor expressed as the same tumour antigen. This provided the effective, clinical treatment for the multi-drug resistance tumour.

ABSTRACT

Cytokine-induced killer cells (CIK) are capable of lysing tumor cell and recognizing these cells in a non-MHC restricted fashion. After they were co-cultured with Dendritic cells (DC) loaded multidrug resistance tumor antigen, do they have the higher antitumor effect to the same multidrug resistance tumor?

Accepted: 
11 Sep, 2015
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 03 Nov, 2015

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Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

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