nitrate reductase assay

Detection of Drug Resistant Mycobacterium tuberculosis among Patients with and without HIV Infection in a Rural Setting

Issue:

Vol 62, Issue 2: Feb (2013)

DOI:

10.7727/wimj.2012.082

Pages:

122–6

Synopsis:

This research establishes the sensitivity of the Griess nitrate reductase assay (NRA) and the Hain molecular line probe assay (LPA) in tuberculosis (TB)/HIV coinfected patients in Guyana. It also highlights the difference in sensitivities of the two drug susceptibility tests.

ABSTRACT

Objective: To analyse the sensitivity of Mycobacterium tuberculosis by nitrate reductase assay (NRA) and the Hain molecular line probe assay (LPA) in sputa of tuberculosis (TB)/HIV co-infected patients in Guyana.

Design: Sputum samples were collected from known TB patients at Georgetown Chest Clinic and were analysed at the Reference Laboratory, Guyana, over the period April 2010 to April 2011.

Received:

10 Jul, 2012

Accepted:

11 May, 2012

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