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DN Ignacio

A Bio-computing Analysis of the Resting-to-pulsed Conformational Changes in Cytochrome c Oxidase

Issue: 
DOI: 
10.7727/wimjopen.2015.090
Pages: 
109–14
Synopsis: 
Cytochrome c oxidase catalyses the reduction of oxygen to water at two vastly different rates determined by the prevailing conformation. We employed bio-computing to view the enzyme’s oxygen/ligand binding site but found no evidence that this site cycles between an opened and closed position as predicted by others.

ABSTRACT

Accepted: 
March 26, 2015
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