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X Wang

Expression and Location of Glucose-regulated Protein 78 in Testis and Epididymis

Issue: 
DOI: 
10.7727/wimjopen.2013.259
Pages: 
14–7
Synopsis: 
GRP78 protein is widely present in human testis, epididymis and spermatozoa. Capacitation and acrosome reaction didn’t affect the location of GRP78. Positioning percentage and signal intensity of GRP78 on sperm were significant positive correlation with sperm progressive motility and vitality.
ABSTRACT
 
Objective: To know the role of glucose-regulated protein 78 (GRP78/BiP/HSPA5) in spermatogenesis and its expression and location in the testis and epididymis.
Methods: Immunohistochemistry and Western blot were used to detect GRP78 location and expression in the testis and epididymis.
Accepted: 
February 24, 2014
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Journal Sections: 

Role of Different Concentrations of Morphine after Coronary Perfusion for Myocardial Protection

Issue: 
DOI: 
10.7727/wimjopen.2013.307
Pages: 
107–10
Synopsis: 
Morphine at concentrations of 2 μmol/L and 4 μmol/L after coronary perfusion on cardiac valve replacement with cardiopulmonary bypass has myocardial protection.

ABSTRACT

Objective: To investigate whether the different concentrations of morphine after coronary perfusion have myocardial protection.

Accepted: 
November 26, 2013
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Journal Sections: 

Clinical Pathology and Prognostic Analysis of Visceral Metastatic Carcinoma of Unknown Primary Site (VMCUP)

Issue: 
DOI: 
10.7727/wimjopen.2013.282
Pages: 
117–120b
Synopsis: 
Comprehensive treatments for visceral metastatic carcinoma of unknown primary site (VMCUP) including surgery and chemotherapy significantly improved patients’ overall survival time. Patients treated mainly by surgery lived longer than those treated by chemotherapy alone. More chemotherapy cycles resulted in longer survival time for patients only receiving chemotherapy. For the first time, this study identified paclitaxel plus fluorouracil as more effective first-line chemotherapy drugs than 5-fluorouracil in treating VMCUP.

ABSTRACT

Objective: To analyse the clinicopathologic characteristics of visceral metastatic carcinoma of unknown primary site (VMCUP), discuss the relationship between its treatment and prognosis, and provide the basis for individualized clinical diagnosis and treatment.

Accepted: 
December 11, 2013
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Journal Sections: 
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