Epididymis

Expression and Location of Glucose-regulated Protein 78 in Testis and Epididymis

Issue:

Vol 1, Issue 1 (2014)

DOI:

10.7727/wimjopen.2013.259

Pages:

14–7

Synopsis:

GRP78 protein is widely present in human testis, epididymis and spermatozoa. Capacitation and acrosome reaction didn’t affect the location of GRP78. Positioning percentage and signal intensity of GRP78 on sperm were significant positive correlation with sperm progressive motility and vitality.

ABSTRACT

Objective: To know the role of glucose-regulated protein 78 (GRP78/BiP/HSPA5) in spermatogenesis and its expression and location in the testis and epididymis.

Methods: Immunohistochemistry and Western blot were used to detect GRP78 location and expression in the testis and epididymis.

Received:

September 18, 2013

Accepted:

February 24, 2014

Published:

April 7, 2014

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