De novo CD5-positive (CD5+) diffuse large B-cell lymphoma (DLBCL) is a highly aggressive subtype of DLBCL with a high incidence of misdiagnosis when spinal cord compression is the initial symptom. We report a case of a 45-year old man with de novo CD5+ DLBCL primarily presenting as spinal cord compression. Unfortunately, this patient was resistant to rituximab-based therapy, which indicated a poor prognosis.
Primary renal lymphoma is very rare. The prognosis is usually poor with median survival less than a year. We report a case in a 55-year old man with a mass in the left kidney detected by ultrasonography and computed tomography. Radical nephrectomy was performed under a preliminary diagnosis of renal cell carcinoma. After the surgery, four courses of chemotherapy were performed. Prognosis may have improved since those reports in the earlier medical literature.