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Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis at the University Hospital of the West Indies, Jamaica

Journal Authors: 
Issue: 
DOI: 
10.7727/wimj.2013.031
Pages: 
589–92
ABSTRACT
 
Objective: Stevens-Johnson syndrome and toxic epidermal necrolysis are uncommon acute der-matologic disorders. The purpose of this study was to examine the frequency, aetiology and outcome of cases of Stevens-Johnson syndrome and toxic epidermal necrolysis admitted to the dermatology ward at the University Hospital of the West Indies.
 
Methods: This was a retrospective study looking at all patients who were admitted with a diagnosis of Stevens-Johnson syndrome, Stevens-Johnson syndrome/toxic epidermal necrolysis overlap syndrome and toxic epidermal necrolysis over a nine-year period.
 
Results: The results showed almost equal numbers of males and females.  The drugs most commonly implicated were phenytoin and cotrimoxazole.  The most common complications were hepatic impair-ment and ophthalmic complications.
 
Conclusion: Stevens-Johnson syndrome and toxic epidermal necrolysis contribute significantly to morbidity and mortality of patients on the dermatology ward although mortality was low compared to other studies.
 
 
Accepted: 
14 Feb, 2013
PDF Attachment: 
Weight: 
-1
e-Published: 22 Jan, 2014
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