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The Role of Mean Platelet Volume as an Inflammatory Marker in Children with Allergic Rhinitis

DOI: 
10.7727/wimj.2015.266

 ABSTRACT

Objective: Mean platelet volume (MPV) is a potential marker of platelet reactivity. Increased MPV levels are shown to be the predictor of inflammation. The aim of this study was to investigate whether MPV is an inflammatory indicator in children with allergic rhinitis.

Methods: The study included 44 children with allergic rhinitis between the ages of six and 18 (47.1% boys), and 45 healthy children between the ages of six and 18 (52.9% boys), and the MPV, PLT, WBC, Hb values in their haemograms were compared.

Results: No differences were found between the allergic rhinitis group and the healthy control group in terms of age and gender (p = 0.15 and 0.60, respectively). While the mean platelet volume (MPV) value of the patient group was 6.9 fL (6–9), the MVP value of the control group was 7.0 fL (5.9–9.7). There was no statistically significant between the patient and control groups in terms of MPV values (p = 0.15). In addition, there were no differences between the patient and control groups in terms of platelet count, leukocyte count, or haemoglobin values (p = 0.09, 0.55 and 0.22, respectively).

Conclusion: To the best of our knowledge, this is the first study to analyze the role of MPV as an inflammatory indicator in children with allergic rhinitis. According to our results, MPV can not be used as an indicator of inflammation in patients with allergic rhinitis.

Accepted: 
04 Jun, 2015
PDF Attachment: 
e-Published: 23 Nov, 2015

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