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Inflammation

An Investigation of Serum Magnesium and Red Blood Cell Distribution Width Values in Patients with Obstructive Sleep Apnea Syndrome

DOI: 
10.7727/wimj.2017.153
Synopsis: 
The study investigated the serum levels of magnesium and red blood cell distribution width (RDW) values and their relationship with polysomnographic parameters in patients with OSAS. Serum RDW values were significantly elevated and magnesium levels were significantly decreased in OSAS. Also, RDW was positively and magnesium was negatively correlated with polysomnographic parameters. To our knowledge, this was the first study investigating the association between RDW and Mg levels in the same patient population.

ABSTRACT

Objective: Obstructive Sleep Apnea Syndrome (OSAS) leads to complications in several systems. The purpose of this study was to examine serum magnesium and red cell distribution width (RDW) values in OSAS, a chronic inflammation, and thus to reveal the relations between these two parameters and with other sleep parameters.

Accepted: 
20 Dec, 2017
Journal Sections: 
e-Published: 22 Dec, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

NKILA: A New LncRNA Regulates the Pro-inflammation Functions of NF-κB

DOI: 
10.7727/wimj.2015.541
Synopsis: 
Abnormal activation of NF-κB signalling pathway plays a crucial role in cancer inflammation. In Cancer Cell, Liu et al, identify a novel lncRNA, NKILA, that is a negative feedback regulator of NF-κB, thus represses NF-κB signalling and cancer-associated inflammation.

INTRODUCTION

Accepted: 
16 Nov, 2015
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 01 Apr, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Importance of Smoking in Pulmonary Involvement of Rheumatoid Arthritis

DOI: 
10.7727/wimj.2015.568
Synopsis: 
Rheumatoid arthritis (RA), is a multi-systemic disease of unknown origin. The reason for the prominence of lungs involvement in some patients with the disease is not clearly defined. Since it was believed that smoking plays an important role in both etiology and progression of the disease, we evaluated the effects of smoking on disease activity, pulmonary functions and alveolar inflammation parameters in patients with RA.

ABSTRACT

Objectives:  The aim of this study was to evaluate the effect of smoking on disease activity and pulmonary involvement in patients with rheumatoid arthritis (RA).  

Accepted: 
08 Feb, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 31 Mar, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Diagnostic Value of Neutrophil Lymphocyte Ratio in Allergy Patients

DOI: 
10.7727/wimj.2015.242
Synopsis: 
This study was conducted to investigate the association between NLR and the progression of the disease in the cases of acute allergic reactions. The significantly high NLR in acute allergic reaction cases in this study suggests that it may be a useful diagnostic parameter in allergic reactions.

ABSTRACT

Objectives: We aimed to investigate the relationship between the neutrophil/lymphocyte ratio (NLR) and clinical characteristics of acute allergic reaction patients diagnosed in an emergency clinic

Material and methods: The medical records of the patients with a diagnosis of acute allergic reaction that presented to Dicle University Medical Faculty Hospital Emergency Department

Accepted: 
10 Aug, 2015
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 18 Dec, 2015

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

The Role of Mean Platelet Volume as an Inflammatory Marker in Children with Allergic Rhinitis

DOI: 
10.7727/wimj.2015.266
Synopsis: 
Although platelets are known to participate actively in both allergic and non-allergic types of inflammation, the mean platelet volume cannot be used as an indicator of inflammation in children with allergic rhinitis.

 ABSTRACT

Objective: Mean platelet volume (MPV) is a potential marker of platelet reactivity. Increased MPV levels are shown to be the predictor of inflammation. The aim of this study was to investigate whether MPV is an inflammatory indicator in children with allergic rhinitis.

Accepted: 
04 Jun, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 23 Nov, 2015

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Investigation of the Anti-inflammatory and Analgesic Effects of the Aqueous Extract Obtained from the Bark of Guiacum Officinale (Lignum Vitae)

Issue: 
DOI: 
10.7727/wimj.2015.089
Pages: 
593–97
Synopsis: 
The bark of Guiacum Officinale (Lignum Vitae) is commonly used in folklore practice in Jamaica as a tea preparation to reduce inflammation and pain in knee joints. This study investigated and validated these claims and confirms no toxic effects within 24 hours at the doses used.

 ABSTRACT

Accepted: 
26 Mar, 2015
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Journal Authors: 
e-Published: 04 Nov, 2015

Evaluation of Neutrophil to Lymphocyte Ratio and Monocyte to Lymphocyte Ratio in Gouty Arthritis Attacks

DOI: 
10.7727/wimj.2015.345
Synopsis: 
Gout is an auto-inflammatory disease caused by accumulation of monosodium urate crystals in tissues and organs due to hyperuricemia. Neutrophils, lymphocytes, and monocytes play a role in acute gouty arthritis (AGA) pathogenesis, directly or indirectly, and/or via complex interaction between them. Ratios between these immune system elements have been listed in inflammatory markers which have been used more frequently recently. The present study is the first one to evaluate NLR and MLR in gout, and to investigate the correlation between these and AGA. We found that NLR and MLR were higher in AGA patients when compared with patients in remission and controls, and they had correlations with other inflammatory markers, which suggested a possible correlation with AGA. In conclusion, NLR and MLR values could be used as a cheap and useful inflammatory marker to predict arthritis attacks in patients with gout.

ABSTRACT

Objective: To evaluate neutrophil to lymphocyte ratio (NLR) and monocyte to lymphocyte ratio (MLR) in patients with gouty arthritis.

Accepted: 
21 Aug, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 15 Oct, 2015

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Antidepressant-like Effect of EGb 761 in Rats with Chronic Mild Stress-induced Depressive Behaviors

DOI: 
10.7727/wimj.2015.087
Synopsis: 
EGb 761 possesses antidepressant activity in rats exposed to CMS. Besides, it can partially reverse the alterations of IL-1β, IL-6, VEGF and HPA axis dysfunction induced by CMS in rats.

ABSTRACT

Objective: The aims were to investigate the effects of EGb 761 on depressive behaviors in rats exposed to chronic mild stress (CMS) and the possible mechanisms of the actions.

Accepted: 
26 Mar, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 18 Sep, 2015

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Circulating Adipokine Levels in Non-diabetic Subjects with High Normal Blood Pressure

Issue: 
DOI: 
10.7727/wimj.2014.332
Pages: 
260–2
Synopsis: 
Adipokines are adipocyte-secreted peptides that are involved in several pathways that lead to insulin resistance, inflammation, atherosclerosis and cardiovascular disease. Increased levels of resistin and/or decreased levels of adiponectin are associated with cardiovascular mortality and the development of hypertension.

ABSTRACT

Objective: This study aimed to evaluate the levels of the adipokines, resistin and adiponectin in normotensive and high normal blood pressure patients.

Accepted: 
25 Mar, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 23 Nov, 2015

Anti-RA 33: A Marker of Good Prognosis in Seronegative Rheumatoid Arthritis

DOI: 
10.7727/wimj.2016.330
Synopsis: 
We investigated the diagnosis capability and extent of Anti-RA 33 positivity and clinical characteristics in patients with RA. We highlight a strong negative correlation between Anti-RA 33 positivity and the quality of life. Anti-RA 33 antibodies may exert helpful effects determining prognosis in established RA patients though have poor diagnostic capability.

ABSTRACT

Objective: Autoantibodies are evident in the early stages of rheumatoid arthritis (RA) and play important roles in diagnosis. The aim of this study was to investigate the diagnosis capability and extent of Anti-RA 33 positivity and clinical characteristics in patients with RA.

Accepted: 
22 Aug, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 07 Sep, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

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