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Inflammation

An Investigation of Serum Magnesium and Red Blood Cell Distribution Width Values in Patients with Obstructive Sleep Apnoea Syndrome

Issue: 
Vol 71, Issue 1: 2024
DOI: 
10.7727/wimj.2017.153
Pages: 
58-62
Synopsis: 
The study investigated the serum levels of magnesium and red blood cell distribution width (RDW) values and their relationship with polysomnographic parameters in patients with Obstructive sleep apnoea syndrome (OSAS). Serum RDW values were significantly elevated and magnesium levels were significantly decreased in OSAS. Also, RDW was positively and magnesium was negatively correlated with polysomnographic parameters. To our knowledge, this was the first study investigating the association between RDW and Mg levels in the same patient population.

ABSTRACT

Objective: Obstructive sleep apnoea syndrome (OSAS) leads to complications in several systems. The purpose of this study was to examine serum magnesium and red cell distribution width (RDW) values in OSAS, a chronic inflammation, and thus to reveal the relations between these two parameters and with other sleep parameters.

Received: 
25 Jul, 2017
Accepted: 
20 Dec, 2017
Published: 
30 Mar, 2024
PDF Attachment: 
PDF icon wimj-iss1-2024_58_62.pdf
Journal Sections: 
Original Articles
Keywords: 
Inflammation
magnesium
obstructive sleep apnoea syndrome
red blood cell distribution width.
Journal Authors: 
K Kilic
MS Sakat
O Araz
MS Gozeler
e-Published: 22 Dec, 2017

Anti-RA 33: A Marker of Good Prognosis in Seronegative Rheumatoid Arthritis

Issue: 
Vol 69, Issue 9: 2023
DOI: 
10.7727/wimj.2016.330
Pages: 
617-23
Synopsis: 
We investigated the diagnosis capability and extent of anti-RA 33 positivity and clinical characteristics in patients with rheumatoid arthritis (RA). We highlight a strong negative correlation between anti-RA 33 positivity and the quality of life. Anti-RA 33 antibodies may exert helpful effects determining prognosis in established RA patients though have poor diagnostic capability.

ABSTRACT

Objective: Autoantibodies are evident in the early stages of rheumatoid arthritis (RA) and play important roles in diagnosis. The aim of this study was to investigate the diagnostic capability and extent of anti-RA 33 positivity and clinical characteristics in patients with RA.

Received: 
30 Jun, 2016
Accepted: 
22 Aug, 2016
Published: 
25 Jan, 2023
PDF Attachment: 
PDF icon wimj-iss9-2023_617_623.pdf
Journal Sections: 
Original Articles
Keywords: 
Inflammation
prognostic factor
rheumatoid arthritis.
Journal Authors: 
H Harman
E Karakeçe
MS Sağ
İ Tekeoğlu
İH Çiftçi
e-Published: 07 Sep, 2016

NKILA: A New LncRNA Regulates the Pro-inflammation Functions of NF-κB

DOI: 
10.7727/wimj.2015.541
Synopsis: 
Abnormal activation of NF-κB signalling pathway plays a crucial role in cancer inflammation. In Cancer Cell, Liu et al, identify a novel lncRNA, NKILA, that is a negative feedback regulator of NF-κB, thus represses NF-κB signalling and cancer-associated inflammation.

INTRODUCTION

Received: 
10 Nov, 2015
Accepted: 
16 Nov, 2015
PDF Attachment: 
PDF icon yan_et_al-lncrna_nkila_regulates_inflammation.pdf
Journal Sections: 
Commentary
Keywords: 
cancer
Inflammation
IncRNA
nf-Kb
Journal Authors: 
Y Yan
Z Xu
Z Li
Z Gong
e-Published: 01 Apr, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Importance of Smoking in Pulmonary Involvement of Rheumatoid Arthritis

DOI: 
10.7727/wimj.2015.568
Synopsis: 
Rheumatoid arthritis (RA), is a multi-systemic disease of unknown origin. The reason for the prominence of lungs involvement in some patients with the disease is not clearly defined. Since it was believed that smoking plays an important role in both etiology and progression of the disease, we evaluated the effects of smoking on disease activity, pulmonary functions and alveolar inflammation parameters in patients with RA.

ABSTRACT

Objectives:  The aim of this study was to evaluate the effect of smoking on disease activity and pulmonary involvement in patients with rheumatoid arthritis (RA).  

Received: 
24 Nov, 2015
Accepted: 
08 Feb, 2016
PDF Attachment: 
PDF icon balaban_et_al-smoking_and_rheumatoid_arthritis.pdf
Journal Sections: 
Original Articles
Keywords: 
Smoking
Inflammation
Rheumatoid Arthritis
Anti-CCP
bronchoalveolar lavage
Journal Authors: 
A Balaban
I Basyigit
A Cefle
H Boyaci
F Yildiz
S Baris
G Gacar
e-Published: 31 Mar, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Diagnostic Value of Neutrophil-to-Lymphocyte Ratio in Allergy Patients

Issue: 
Vol 69, Issue 4: 2021
DOI: 
10.7727/wimj.2015.242
Pages: 
227-9
Synopsis: 
This study was conducted to investigate the association between neutrophil lymphocyte ratio (NLR) and the progression of the disease in the cases of acute allergic reactions. The significantly high NLR in acute allergic reaction cases in this study suggests that it may be a useful diagnostic parameter in allergic reactions.

ABSTRACT

Objective: To investigate the relationship between the neutrophil-to-lymphocyte ratio (NLR) and the clinical characteristics of the acute allergic reaction patients diagnosed in an emergency clinic.

Received: 
18 May, 2015
Accepted: 
10 Aug, 2015
Published: 
15 Oct, 2021
PDF Attachment: 
PDF icon wimj-iss4-2021_227_229.pdf
Journal Sections: 
Original Articles
Keywords: 
allergy
Inflammation
neutrophil-to-lymphocyte ratio
Journal Authors: 
B Elbey
ÜC Yazgan
Y Zengin
e-Published: 18 Dec, 2015

The Role of Mean Platelet Volume as an Inflammatory Marker in Children with Allergic Rhinitis

Issue: 
Vol 69, Issue 6: 2021
DOI: 
10.7727/wimj.2015.266
Pages: 
395-8
Synopsis: 
Although platelets are known to participate actively in both allergic and non-allergic types of inflammation, the mean platelet volume cannot be used as an indicator of inflammation in children with allergic rhinitis.

 ABSTRACT

Objective: The mean platelet volume (MPV) is a potential marker of platelet reactivity. Increased MPV levels are shown to be the predictors of inflammations. The aim of this study was to investigate whether MPV is an inflammatory indicator in children with allergic rhinitis.

Received: 
21 May, 2015
Accepted: 
04 Jun, 2015
Published: 
10 Dec, 2021
PDF Attachment: 
PDF icon wimj-iss6-2021_395_398.pdf
Journal Sections: 
Original Articles
Keywords: 
Allergic rhinitis
children
Inflammation
mean platelet volume.
Journal Authors: 
S Kutluğ
A Söğüt
Ş Paksu
R Sancak
N Murat
E Günbey
R Karli
e-Published: 23 Nov, 2015

Circulating Adipokine Levels in Non-diabetic Subjects with High Normal Blood Pressure

Issue: 
Vol 65, Issue 2: 2016
DOI: 
10.7727/wimj.2014.332
Pages: 
260–2
Synopsis: 
Adipokines are adipocyte-secreted peptides that are involved in several pathways that lead to insulin resistance, inflammation, atherosclerosis and cardiovascular disease. Increased levels of resistin and/or decreased levels of adiponectin are associated with cardiovascular mortality and the development of hypertension.

ABSTRACT

Objective: This study aimed to evaluate the levels of the adipokines, resistin and adiponectin in normotensive and high normal blood pressure patients.

Received: 
21 Nov, 2014
Accepted: 
25 Mar, 2015
PDF Attachment: 
PDF icon wimj_iss2_2016_260-62.pdf
Journal Sections: 
Original Articles
Keywords: 
Inflammation
Adiponectin
high normal blood pressure
resistin
Journal Authors: 
AF Rubio-Guerra
H Vargas-Robles
MB Durán-Salgado
JJ Lozano-Nuevo
G Vargas-Ayala
BA Escalante-Acosta
e-Published: 23 Nov, 2015

Investigation of the Anti-inflammatory and Analgesic Effects of the Aqueous Extract Obtained from the Bark of Guiacum Officinale (Lignum Vitae)

Issue: 
Vol 66, Issue 6: 2017
DOI: 
10.7727/wimj.2015.089
Pages: 
593–97
Synopsis: 
The bark of Guiacum Officinale (Lignum Vitae) is commonly used in folklore practice in Jamaica as a tea preparation to reduce inflammation and pain in knee joints. This study investigated and validated these claims and confirms no toxic effects within 24 hours at the doses used.

 ABSTRACT

Received: 
23 Feb, 2015
Accepted: 
26 Mar, 2015
Published: 
20 Dec, 2018
PDF Attachment: 
PDF icon wimj-iss6-2017_593_597.pdf
Journal Sections: 
Original Articles
Keywords: 
Analgesia
Extract
Guaiacum officinale
Inflammation
Lignum vitae
Journal Authors: 
K Williams
AS Jacob
SA Levy
e-Published: 04 Nov, 2015

Evaluation of Neutrophil-to-Lymphocyte Ratio and Monocyte-to-Lymphocyte Ratio in Gouty Arthritis Attacks

Issue: 
Vol 69, Issue 9: 2023
DOI: 
10.7727/wimj.2015.345
Pages: 
612-6
Synopsis: 
Gout is an auto-inflammatory disease caused by accumulation of monosodium urate crystals in tissues and organs due to hyperuricemia. Neutrophils, lymphocytes and monocytes play a role in acute gouty arthritis (AGA) pathogenesis, directly or indirectly, and/or via complex interaction between them. Ratios between these immune system elements have been listed in inflammatory markers which have been used more frequently recently. The present study is the first one to evaluate neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio (MLR) in gout, and to investigate the correlation between these and AGA. We found that NLR and MLR were higher in AGA patients when compared with patients in remission and controls, and they had correlations with other inflammatory markers, which suggested a possible correlation with AGA. In conclusion, NLR and MLR values could be used as a cheap and useful inflammatory marker to predict arthritis attacks in patients with gout.

ABSTRACT

Objective: To evaluate neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio (MLR) in patients with gouty arthritis.

Received: 
25 Jun, 2015
Accepted: 
21 Aug, 2015
Published: 
25 Jan, 2023
PDF Attachment: 
PDF icon wimj-iss9-2023_612_616.pdf
Journal Sections: 
Original Articles
Keywords: 
Arthritis attack
gout
Inflammation
monocytes-to-lymphocyte ratio
neutrophil-to-lymphocyte ratio.
Journal Authors: 
A Şahin
AU Uslu
D Seven
A Camci
Ö Demirpençe
M Şahin
T Uncu
B Aydın
e-Published: 15 Oct, 2015

Antidepressant-like Effect of EGb 761 in Rats with Chronic Mild Stress-induced Depressive Behaviors

DOI: 
10.7727/wimj.2015.087
Synopsis: 
EGb 761 possesses antidepressant activity in rats exposed to CMS. Besides, it can partially reverse the alterations of IL-1β, IL-6, VEGF and HPA axis dysfunction induced by CMS in rats.

ABSTRACT

Objective: The aims were to investigate the effects of EGb 761 on depressive behaviors in rats exposed to chronic mild stress (CMS) and the possible mechanisms of the actions.

Received: 
23 Feb, 2015
Accepted: 
26 Mar, 2015
PDF Attachment: 
PDF icon hua_et_al-antidepressant-like_effect_of_egb_761.pdf
Journal Sections: 
Original Articles
Keywords: 
Depression
Inflammation
Antidepressant-like effect
chronic mild stress
EGb 761
HPA axis
VEGF
Journal Authors: 
L Hua
L Limei
W Chunyan
L Zhonggang
Y Kuitao
e-Published: 18 Sep, 2015

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

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West Indian Medical Journal

Faculty of Medical Sciences,
The University of the West Indies,
Mona, Kingston 7
Tel: (876) 927-1214
Fax: (876) 927-1846
wimj@uwimona.edu.jm
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