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The Effects of Ingested Aluminium on Brain Cytochrome Oxidase Activity

Issue: 
Pages: 
422–7
Synopsis: 
When rabbits were maintained on a diet supplemented with aluminium, a 35% decrease in brain cytochrome c oxidase activity (COX) was observed. Isolation of number of the enzyme’s low molecular weight subunits was absent.

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e-Published: 20 Sep, 2013

Elevated Ferric, Calcium and Magnesium Ions in the Brain Induce Protein Aggregation in Brain Mitochondria

Issue: 
Pages: 
122–7
Synopsis: 
This study evaluated the impact of elevated aluminum, ferric, calcium and magnesium ions on rabbit brain. Aluminum ion, but not the others, induced neurofibrillary degeneration within the midbrain and medulla. On the other hand, the other three ions caused aggregation of low molecular weight mitochondrial proteins.

 

ABSTRACT

Objective: Alzheimer’s disease and Parkinson’s disease are two of several neurodegenerative disorders that affect the elderly. Although their aetiology remains uncertain, studies suggest that elevated aluminium or other metal ions in the brain directly influence the development of the histological abnormalities normally associated with these diseases; other investigations suggest that metal-ioninduced-dysfunction of mitochondria might be a critical factor.

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e-Published: 19 Aug, 2013

Single Photon Emission Computerized Tomography in the Evaluation of the Osteoblastic Activities of a New Bone Regeneration Technique, Analysis of 12 Mandibular Sites in six Experimental Pigs

Single Photon Emission Computerized Tomography and Histological Evaluation in the Validation of a New Technique for Closure of Oro-antral Communication An Experimental Study in Pigs

Issue: 
Pages: 
166–72
Synopsis: 
The Sandwich Technique for closure of oro-antral communication results in vascularized new bone formation which eventually osseo-intergrates with surrounding bone.


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e-Published: 18 Jul, 2013

Marginally Low Copper Causes Lesions of the Midbrain in Animal Models: The Implications for Man

Issue: 
Pages: 
481–6
Synopsis: 
There were pathological changes in the midbrain of young sheep and rabbit with low serum copper.

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e-Published: 04 Jul, 2013
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