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Comparison of the Effect of Granulocyte-Macrophage Colony Stimulating Factor by Intranasal and Subcutaneous Injection for Traumatic Brain Injury in Rats

Issue: 
DOI: 
10.7727/wimj.2016.251
Synopsis: 
Analogous adult stem cells may be a protocol of treatment for traumatic brain injury (TBI). This study found that intranasal delivery of Granulocyte-macrophage colony stimulating factor provides a potential protective effects in traumatic brain injury.

ABSTRACT

Background: Recent studies have shown that autologous adult stem cells may be a strategy for treatment of traumatic brain injury (TBI) in humans. The purpose of this study was to explore the effect of autologous bone marrow stem cell mobilization induced by intranasal administration of granulocyte-macrophage colony stimulating factor (GM-CSF) for TBI in rats.

Accepted: 
22 Aug, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 07 Apr, 2017

Pre-published Manuscript

This manuscript has been assigned to a volume and issue but has not yet been published. It is either being edited, typeset or is in the proof stage of publication.
In the pre-published stage, this manuscript may contain statements, opinions, and information that have errors in facts, figures, or interpretation. Any final changes in this manuscript will be made at the time of publication and will be reflected in the final electronic version of the issue. The editors and authors and their respective employees are not responsible or liable for the use of any such inaccurate or misleading data, opinion or information contained in the articles in this section.

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