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D Xu

Chicken Collagen Type II Reduces Articular Cartilage Destruction in a Model of Osteoarthritis in Rats

Issue: 
Pages: 
202–7
Synopsis: 
Oral Chicken Collagen Type II may be a potent drug candidate for osteoarthritis treatment.

ABSTRACT

Aim: To evaluate the therapeutic effects of domestic chicken collagen type II (CCII) on rat osteoarthritis (OA) and analyze concomitant changes in the level of Matrix metalloproteinase (MMP)-13, MMP-9, Cathepsin K and their mRNA as well as the tissue inhibitor of matrix metalloproteinase (TIMP)-1 mRNA in articular cartilage of osteoarthritic rats.

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e-Published: 02 Jul, 2013
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