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G Horta-Baas

Expectations of Treatment of Hepatitis C in Children

DOI: 
10.7727/wimj.2016.153
Synopsis: 
The study aimed at presenting a general overview of the current treatments for HCV infection in children. In children the most commonly used drugs are pegylated alpha interferon in combination with ribavirin only Boceprevir was tested and not approved for use in children. Safety and efficacy of new drugs in children need further investigation.

ABSTRACT

Background: HCV infection in children differs from infection in adult through transmission paths, spontaneous viral clearance rate, and fibrosis progression duration of chronic infection. It is estimated that the rate of children with chronic hepatitis C will develop cirrhosis is less than 2%, however there are reports of children requiring liver transplantation. 

Accepted: 
25 May, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 14 Jul, 2016

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Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

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