HO Ogefere

Correlation of CD4 Count with Platelet Count, Prothrombin Time and Activated Partial Thromboplastin Time among HIV Patients in Benin City, Nigeria

Issue:

Vol 58, Issue 5 (2009)

Pages:

437–40

Synopsis:

This study reveals that platelet count did not correlate with CD4 count of HIV patients. Only PT correlated with CD4 count and the correlation was observed only amongst HIV patients with CD4 count < 200/μL. Endothelial activation was suggested as the possible reason.

ABSTRACT

Objective: To determine the effect of CD4 count on platelet count, prothrombin time (PT) and activated partial thromboplastin time (APTT) among HIV patients.

Method: Blood samples were collected from 100 subjects consisting of 70 HIV treatment naive patients and 30 HIV seronegative individuals. Platelet count, CD4 count, PT and APTT were performed on the blood samples using standard techniques.

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