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K Ren

Protective Effects of Liquiritin on the Brain of Rats with Alzheimer’s Disease

Issue: 
DOI: 
10.7727/wimj.2016.058
Pages: 
468–72
Synopsis: 
Alzheimer’s disease (AD) is clinically manifested by progressive memory damage and cognitive dysfunction. In this study, a rat AD model with liquiritin (LQ) interference was established to observe the effects of LQ on the AD rats’ behavioural memory. The protective and antioxidant effects of LQ improved the rats’ learning and memory ability.

ABSTRACT

Background: Alzheimer’s disease (AD) is a sort of nerve degenerative disease with clinical manifestation of memory damage and cognitive dysfunction. Its typical pathological change is the abnormal deposition of amyloid-beta (Aβ).  

Method: In this study, a rat AD model with liquiritin (LQ) interference was established to observe the effects of LQ on the AD rats’ behavioural memory and primary hippocampus cells.  

Accepted: 
08 Feb, 2016
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e-Published: 18 Apr, 2016
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