Chronic hepatitis B

The Diagnostic Value of FibroScan in Assessing Significant Liver Fibrosis in Patients with Chronic Hepatitis B

Issue:

Vol 65, Issue 1: 2016

DOI:

10.7727/wimj.2014.150

Pages:

106–10

Synopsis:

This study assesses the value of Fibroscan and fibrosis serum models, including aspartate transaminase to platelet ratio index (APRI), in predicting significant liver fibrosis in patients with chronic hepatitis B infection compared with liver biopsy.

ABSTRACT

Objective: Significant liver fibrosis is recognized as the key link of therapy and prognosis in patients with chronic hepatitis B infection (CHB). The present study is designed to estimate the benefits of FibroScan (FS) in diagnosing significant fibrosis in patients with CHB.

Received:

17 Jun, 2014

Accepted:

30 Jun, 2014

PDF Attachment:

wimj_iss1_2016_106_110.pdf

Journal Sections:

Original Articles

Keywords:

Chronic hepatitis B

FibroScan

liver stiffness measurement

liver biopsy

non-invasive

significant liver fibrosis

Journal Authors:

e-Published: 15 May, 2015

Read more about The Diagnostic Value of FibroScan in Assessing Significant Liver Fibrosis in Patients with Chronic Hepatitis B

Investigation by the Method of INNO-LiPA of Primary Resistance to Lamivudine in Patients with Chronic Hepatitis B Who Have Not Used Antiviral Therapy

Issue:

Vol 65, Issue 1: 2016

DOI:

10.7727/wimj.2014.291

Pages:

111–5

Synopsis:

Lamivudine, an effective oral antiviral agent, inhibits the replication of hepatitis B virus by blocking reverse transcriptase enzyme. Administering lamivudine is an effective and convenient method of early treatment.

ABSTRACT

Received:

15 Oct, 2014

Accepted:

29 Oct, 2014

PDF Attachment:

wimj_iss1_2016_111_115.pdf

Journal Sections:

Keywords:

Journal Authors:

e-Published: 30 Apr, 2015

Read more about Investigation by the Method of INNO-LiPA of Primary Resistance to Lamivudine in Patients with Chronic Hepatitis B Who Have Not Used Antiviral Therapy

Evaluation of Interleukin-10 Levels in Patients Diagnosed with Chronic Hepatitis

Issue:

Vol 64, Issue 2: March (2015)

DOI:

10.7727/wimj.2014.154

Pages:

71–5

Synopsis:

Interleukin 10 (IL-10) is a cytokine which has anti-inflammatory characteristics. In this study, we evaluated whether IL-10 levels increase when hepatitis B virus DNA levels increase. High levels of IL-10 in chronic hepatitis B patients indicate that it may be the cause of ineffective immune response. Decreasing IL-10 levels by using various methods may have important contributions in progression and treatment of the disease.

ABSTRACT

Objective: One of the most important factors playing a role in chronic hepatitis B pathogenesis is cytokine release and one of the cytokines with anti-inflammatory characteristic is interleukin-10 (IL-10). The aim of the present study is to examine IL-10 levels in patients with chronic hepatitis B.

Received:

17 Jan, 2014

Accepted:

30 Jun, 2014

PDF Attachment:

wimjmar2015_71_75.pdf

Journal Sections:

Keywords: