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Chronic hepatitis B

The Diagnostic Value of FibroScan in Assessing Significant Liver Fibrosis in Patients with Chronic Hepatitis B

Issue: 
DOI: 
10.7727/wimj.2014.150
Pages: 
106–10
Synopsis: 
This study assesses the value of Fibroscan and fibrosis serum models, including aspartate transaminase to platelet ratio index (APRI), in predicting significant liver fibrosis in patients with chronic hepatitis B infection compared with liver biopsy.

ABSTRACT

Objective: Significant liver fibrosis is recognized as the key link of therapy and prognosis in patients with chronic hepatitis B infection (CHB). The present study is designed to estimate the benefits of FibroScan (FS) in diagnosing significant fibrosis in patients with CHB.

Accepted: 
30 Jun, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 15 May, 2015

Investigation by the Method of INNO-LiPA of Primary Resistance to Lamivudine in Patients with Chronic Hepatitis B Who Have Not Used Antiviral Therapy

Issue: 
DOI: 
10.7727/wimj.2014.291
Pages: 
111–5
Synopsis: 
Lamivudine, an effective oral antiviral agent, inhibits the replication of hepatitis B virus by blocking reverse transcriptase enzyme. Administering lamivudine is an effective and convenient method of early treatment.

ABSTRACT

Accepted: 
29 Oct, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 30 Apr, 2015

Evaluation of Interleukin-10 Levels in Patients Diagnosed with Chronic Hepatitis

Issue: 
DOI: 
10.7727/wimj.2014.154
Pages: 
71–5
Synopsis: 
Interleukin 10 (IL-10) is a cytokine which has anti-inflammatory characteristics. In this study, we evaluated whether IL-10 levels increase when hepatitis B virus DNA levels increase. High levels of IL-10 in chronic hepatitis B patients indicate that it may be the cause of ineffective immune response. Decreasing IL-10 levels by using various methods may have important contributions in progression and treatment of the disease.

ABSTRACT

Objective: One of the most important factors playing a role in chronic hepatitis B pathogenesis is cytokine release and one of the cytokines with anti-inflammatory characteristic is interleukin-10 (IL-10). The aim of the present study is to examine IL-10 levels in patients with chronic hepatitis B.

Accepted: 
30 Jun, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 27 Jan, 2015
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