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EGb 761

Antidepressant-like Effect of EGb 761 in Rats with Chronic Mild Stress-induced Depressive Behaviors

EGb 761 possesses antidepressant activity in rats exposed to CMS. Besides, it can partially reverse the alterations of IL-1β, IL-6, VEGF and HPA axis dysfunction induced by CMS in rats.


Objective: The aims were to investigate the effects of EGb 761 on depressive behaviors in rats exposed to chronic mild stress (CMS) and the possible mechanisms of the actions.

26 Mar, 2015
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e-Published: 18 Sep, 2015


Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

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