In this study, we aimed to investigate the serum levels of VEGF and angiopoetin receptor Tie-2 in patient with essential hypertension. A total of 90 individuals were included. The data indicate that serum levels of VEGF and Tie-2 receptor may be related to the primer hypertension.
ABSTRACT
Objective: Hypertension is a common but incompletely understood disease. Emerging evidence supports a novel view of hypertension as a disease of inadequate or aberrant responses to angiogenic factors. In the present study we aimed to investigate the serum levels
of vascular endothelial growth factor (VEGF), an angiogenic factorand soluble angiopoetin receptor Tie-2 (sTie-2) in patient with essential hypertension.
Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.
EGb 761 possesses antidepressant activity in rats exposed to CMS. Besides, it can partially reverse the alterations of IL-1β, IL-6, VEGF and HPA axis dysfunction induced by CMS in rats.
ABSTRACT
Objective: The aims were to investigate the effects of EGb 761 on depressive behaviors in rats exposed to chronic mild stress (CMS) and the possible mechanisms of the actions.
Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.