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exposure duration

Alterations in Gold Nanoparticle Levels Are Size Dependent, with the Smaller Ones Inducing the Most Toxic Effects and Related to the Time of Exposure of the Gold Nanoparticles

Issue: 
DOI: 
10.7727/wimj.2014.350
Pages: 
87–92
Synopsis: 
Our results indicate that the smaller 10 nm gold nanoparticles (GNPs) are mostly taken up and accumulate in different rat organs, suggesting the induced toxic effects which is supported by histological investigation; while the larger 50 nm GNPs are retained in the blood of rats.

ABSTRACT

 

Background: Gold nanoparticle (GNP) levels in the blood of rats in vivo have not been previously documented. This study aimed to evaluate the influence of size and exposure duration of GNPs on the gold levels in the blood of rats in vivo.

Accepted: 
11 Dec, 2014
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 07 May, 2015
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