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gene polymorphism

Cytotoxic T Lymphocyte-associated Antigen 4 Polymorphisms Correlated with Graves’ Disease in Patients of Han Ethnicity in Yunnan, China

Issue: 
DOI: 
10.7727/wimj.2016.026
Pages: 
7-12
Synopsis: 
This study aimed to investigate the correlations between polymorphisms at position 49 in exon 1 and position 318 in the promoter of the cytotoxic T lymphocyte-associated antigen 4 gene and autoimmune thyroid diseases in a Han Chinese population. This had not been reported before.

ABSTRACT

Objective: To investigate the correlations between polymorphisms at position 49 in exon 1 and position 318 in the promoter of the cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) gene and autoimmune thyroid diseases in a Han Chinese population.

Accepted: 
02 Feb, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 01 Mar, 2016

Study of Sex Hormone-binding Globulin Gene Polymorphism and Risk of Type 2 Diabetes Mellitus in Egyptian Men

Issue: 
DOI: 
10.7727/wimj.2014.088
Pages: 
338–43
Synopsis: 
Sex hormone-binding globulin gene polymorphisms are associated with higher risk of Type 2 diabetes mellitus in Egyptian men, through lowering circulating levels of sex hormone-binding globulin and consequently lowering testosterone and elevating oestradiol levels, which may be linked to insulin resistance.

ABSTRACT

Accepted: 
23 Apr, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 15 May, 2015
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