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diabetes mellitus

Chronic Kidney Disease in the Caribbean Island of Antigua: Causes, Morbidity and Mortality Factors

Issue: 
Vol 67, Issue 2: 2018
DOI: 
10.7727/wimj.2017.238
Pages: 
173-84
Synopsis: 
Diabetes mellitus and hypertension, were the most common causes of chronic kidney disease (CKD) among the sampled patients in Antigua while ischaemic heart disease and infections were the major causes of morbidity and mortality among the patients.

ABSTRACT

Background: Chronic kidney disease (CKD) and its associated high morbidity and mortality cause a significant economic burden and decreased quality of life in affected patients in Antigua, the rest of the Caribbean and globally. The causes of CKD in Antigua, morbidity and mortality factors affecting the sampled patients were evaluated with a view to formulating interventions to minimize the occurrence and the impact of these factors.

Received: 
17 Oct, 2017
Accepted: 
01 Nov, 2017
Published: 
25 Jul, 2018
PDF Attachment: 
PDF icon wimj-iss2-2018_173_184.pdf
Journal Sections: 
Renal Forum
Keywords: 
Antigua
Caribbean
chronic kidney disease
diabetes mellitus
Hypertension
Ischaemic heart disease
Journal Authors: 
G Meade
AK Soyibo
M Lawrence-Wright
T Ferguson
I Thomas
e-Published: 07 Dec, 2017

Antidiabetic Potential of Onosma hispidum Roots

DOI: 
10.7727/wimj.2016.436
Synopsis: 
In present study, antidiabetic potential of Onosma hispidum roots were assessed in diabetic animal models. O hispidum roots exhibited antihyperglycemic and antihyperlipidemic effects. In addition, histopathological investigation revealed pancreatic beta cells regeneration activity by plant roots.

ABSTRACT

Objective: To investigate the antihyperglycemic, antihyperlipidemic and pancreatic beta cells regeneration potentials of Onosma hispidum (ratanjot) root extracts in alloxan-induced diabetic rabbits.

Received: 
09 Aug, 2016
Accepted: 
13 Feb, 2017
PDF Attachment: 
PDF icon hussain_et_al-antidiabetic_potential_of_onosma_hispidum.pdf
Journal Sections: 
Original Articles
Keywords: 
diabetes mellitus
Alloxan
antihyperglycemia
Onosma hispidum
pancreatic beta cells
Journal Authors: 
F Hussain
A Ali
M Shahid
e-Published: 02 Mar, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

The Effects on Offspring of Diabetes Mellitus Induced by Chemical Agents in Rats with Advanced Pregnancy

Issue: 
Vol 69, Issue 1: 2021
DOI: 
10.7727/wimj.2015.587
Pages: 
56-9
Synopsis: 
Diabetes is the most important cause of perinatal mortality, and a four- to eight-fold greater malformation rate is observed among babies of diabetic mothers than among the general population. Cardiac anomalies and central nervous system anomalies are the most common anomalies observed in babies of diabetic mothers.

ABSTRACT

Background: Gestational diabetes mellitus is an increasingly frequent metabolic disorder that is important for both baby and mother. New studies on the development and treatment of the disease are required.

Objective: To investigate the effects on offspring’s survival and the biochemical values of diabetes mellitus, induced by different doses of two chemical agents among 35 rats with advanced pregnancy.

Received: 
03 Dec, 2015
Accepted: 
07 Dec, 2015
Published: 
30 Apr, 2021
PDF Attachment: 
PDF icon wimj-iss1-2021_56_59.pdf
Journal Sections: 
Original Articles
Keywords: 
Alloxan
diabetes mellitus
Offspring
rat
streptozotocin
Journal Authors: 
N Canlı
HA Ozkan
A Rısvanli
e-Published: 30 Mar, 2016

A Study of the Association between Diabetes Mellitus and Chronic Hepatitis B Virus Infection

Issue: 
Vol 68, Issue 2: 2019
DOI: 
10.7727/wimj.2015.236
Pages: 
108–14
Synopsis: 
The present study was designed to evaluate the relationship between HBV infection and type 2 diabetes mellitus first time from Pakistan and found that HBV infection did not enhance the risk of diabetes despite the significant differences in the biochemical parameters among the study's sample.

ABSTRACT

Background: Hepatitis B virus (HBV) infection and diabetes mellitus are major health problems associated with significant morbidity and mortality. The published literature suggests an association of diabetes mellitus with liver disease. However, the role of HBV infection in diabetes aetiology is still controversial. The present study was conducted to explore the veracity of this enigmatic association among Pakistani subjects.

Received: 
06 May, 2015
Accepted: 
25 Nov, 2015
Published: 
10 Dec, 2019
PDF Attachment: 
PDF icon wimj-iss2-2019_108_114.pdf
Journal Sections: 
Original Articles
Keywords: 
diabetes mellitus
cirrhosis
hepatitis B
liver disease
Journal Authors: 
M Khurshid
A Rashid
N Aslam
SS Najam
T Siddique
M Islam
M Zain
AR Khan
AA Shah
FR Awan
e-Published: 30 Mar, 2016

Comparative Evaluation of Dyslipaedemia in Obese and Diabetic Patients in Rural and Urban Areas in Lahore, Pakistan

DOI: 
10.7727/wimj.2015.327
Synopsis: 
The present study indicated that combined obesity and diabetes were the major cause of dyslipaedemia and coronary artery disease (CAD) followed by obesity and diabetes. Moreover, the risk of dyslipaedemia and CAD in the urban population, was not significantly different from the rural population.

ABSTRACT

Objective: Obesity and diabetes mellitus are interconnected conditions that share a number of pathophysiological mechanisms such as dyslipidemia leading to cardiovascular complications. The present study was conducted to determine the individual and combined effect of diabetes mellitus and obesity on dyslipidemia and ultimately on silent coronary artery disease (CAD).

Received: 
22 Jun, 2015
Accepted: 
25 Aug, 2015
PDF Attachment: 
PDF icon akhtar_et_al-comparative_evaluation_of_dyslipedemia_in_obese_and_diabetic_patients.pdf
Journal Sections: 
Original Articles
Keywords: 
obesity
diabetes mellitus
coronary artery disease
exercise tolerance test
Journal Authors: 
R Akhtar
H Ahmed
MN Afzal
HR Rehman
I Rashid
S Imran
e-Published: 16 Mar, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Evaluative Research on Pharmacist-managed Diabetes Care: Focus on Self-monitoring of Blood Glucose

Issue: 
Vol 68, Issue 2: 2019
DOI: 
10.7727/wimj.2015.529
Pages: 
101–107
Synopsis: 
This pharmacist evaluative research study (PHARMERS) sought to empower pharmacists to assist in the management of poorly-controlled, diabetic patients. We hoped to demonstrate that patients stand a better chance of achieving improved glycaemic control if closely monitored by a pharmacist.

Abstract

Objective: Pharmacists have not demonstrated the ability to manage chronic diseases such as Type 2 Diabetes Mellitus, which is an ongoing problem in Trinidad and Tobago. The primary objective was to demonstrate that pharmacists can assist patients to achieve at least a 1% decrease in glycosylated haemoglobin (HbA1c ).

Received: 
02 Nov, 2015
Accepted: 
17 Nov, 2015
Published: 
10 Dec, 2019
PDF Attachment: 
PDF icon wimj-iss2-2019_101_107.pdf
Journal Sections: 
Original Articles
Keywords: 
diabetes mellitus
Chronic diseases
glycosylated haemoglobin
managed care
pharmaceutical care
pharmacists
Journal Authors: 
PI Sealy
DN Ignacio
G Legall
e-Published: 15 Mar, 2016

Extrapulmonary Tuberculosis, Multidrug-resistant Tuberculosis and Diabetes Mellitus: Two Cases Highlighting the Need for Clinical Screening for Tuberculosis in Patients with Diabetes Mellitus

Issue: 
Vol 69, Issue 6: 2021
DOI: 
10.7727/wimj.2015.212
Pages: 
429-32

ABSTRACT

Received: 
21 Apr, 2015
Accepted: 
27 Apr, 2015
Published: 
10 Dec, 2021
PDF Attachment: 
PDF icon wimj-iss6-2021_429_432.pdf
Journal Sections: 
Case Reports
Keywords: 
Bidirectional screening
diabetes mellitus
tuberculosis.
Journal Authors: 
OO Sogbanmu
OV Adeniyi
DT Goon
e-Published: 26 Jun, 2015

Study of Sex Hormone-binding Globulin Gene Polymorphism and Risk of Type 2 Diabetes Mellitus in Egyptian Men

Issue: 
Vol 64, Issue 4: September (2015)
DOI: 
10.7727/wimj.2014.088
Pages: 
338–43
Synopsis: 
Sex hormone-binding globulin gene polymorphisms are associated with higher risk of Type 2 diabetes mellitus in Egyptian men, through lowering circulating levels of sex hormone-binding globulin and consequently lowering testosterone and elevating oestradiol levels, which may be linked to insulin resistance.

ABSTRACT

Received: 
07 Apr, 2014
Accepted: 
23 Apr, 2014
PDF Attachment: 
PDF icon wimjsep2015_338_343.pdf
Journal Sections: 
Original Articles
Keywords: 
diabetes mellitus
Egyptian men
estradiol
gene polymorphism
SHBG
testosterone
Journal Authors: 
SA El Tarhouny
SS Zakaria
AM Abdu-Allah
KM Hadhoud
MI Mahmoud
OM Al Nozha
e-Published: 15 May, 2015

Prevalence of Chronic Kidney Disease among Patients Attending a Specialist Diabetes Clinic in Jamaica

Issue: 
Vol 64, Issue 3: June (2015)
DOI: 
10.7727/wimj.2014.084
Pages: 
201–8
Synopsis: 
This study estimated the prevalence of chronic kidney disease (CKD) among patients of the University Hospital of the West Indies diabetes clinic in Jamaica and evaluated the proportion of patients at high risk for adverse outcomes. Approximately 86% of patients had CKD and 70% were at high risk for adverse outcomes.

ABSTRACT

Objective: To estimate the prevalence of chronic kidney disease (CKD) among patients attending the University Hospital of the West Indies (UHWI) Diabetes Clinic and to determine the proportion of patients at high risk for adverse outcomes.

Received: 
07 Apr, 2014
Accepted: 
23 Apr, 2014
PDF Attachment: 
PDF icon wimjjun2015_201_208.pdf
Journal Sections: 
Original Articles
Keywords: 
Jamaica
diabetes mellitus
glomerular filtration rate
chronic kidney disease
Diabetic nephropathy
Albuminuria
Journal Authors: 
TS Ferguson
MK Tulloch-Reid
NO Younger-Coleman
RA Wright-Pascoe
MS Boyne
AK Soyibo
RJ Wilks
e-Published: 04 May, 2015

Antidiabetic Evaluation of Momordica charantia L Fruit Extracts

Issue: 
Vol 63, Issue 4: Aug (2014)
DOI: 
10.7727/wimj.2013.180
Pages: 
294–9
Synopsis: 
Antidiabetic activities (hypoglycaemic, hypolipidaemic and pancreatic beta cells regeneration) of Momordica charantia (MC) fruits were investigated in alloxan diabetic rabbits. Although MC extracts showed significant hypoglycaemic effects (p < 0.05), these did not result in normal glucose and lipid profile levels. Regeneration of pancreatic beta cells by MC extracts was minimal, with fractional improvement produced by glibenclamide.

ABSTRACT

Received: 
27 May, 2013
Accepted: 
29 Oct, 2013
PDF Attachment: 
PDF icon tahira_and_hussain-antidiabetic_evaluation_of_momordica_charantia.pdf
Journal Sections: 
Original Articles
Keywords: 
diabetes mellitus
hyperglycaemia
hyperlipidaemia
Momordica charantia L
Journal Authors: 
S Tahira
F Hussain
e-Published: 08 May, 2014

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West Indian Medical Journal

Faculty of Medical Sciences,
The University of the West Indies,
Mona, Kingston 7
Tel: (876) 927-1214
Fax: (876) 927-1846
wimj@uwimona.edu.jm
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