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diabetes mellitus

Chronic Kidney Disease in the Caribbean Island of Antigua: Causes, Morbidity and Mortality Factors

Issue: 
DOI: 
10.7727/wimj.2017.238
Pages: 
173-84
Synopsis: 
Diabetes mellitus and hypertension, were the most common causes of chronic kidney disease (CKD) among the sampled patients in Antigua while ischaemic heart disease and infections were the major causes of morbidity and mortality among the patients.

ABSTRACT

Background: Chronic kidney disease (CKD) and its associated high morbidity and mortality cause a significant economic burden and decreased quality of life in affected patients in Antigua, the rest of the Caribbean and globally. The causes of CKD in Antigua, morbidity and mortality factors affecting the sampled patients were evaluated with a view to formulating interventions to minimize the occurrence and the impact of these factors.

Accepted: 
01 Nov, 2017
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Journal Sections: 
e-Published: 07 Dec, 2017

Antidiabetic Potential of Onosma hispidum Roots

DOI: 
10.7727/wimj.2016.436
Synopsis: 
In present study, antidiabetic potential of Onosma hispidum roots were assessed in diabetic animal models. O hispidum roots exhibited antihyperglycemic and antihyperlipidemic effects. In addition, histopathological investigation revealed pancreatic beta cells regeneration activity by plant roots.

ABSTRACT

Objective: To investigate the antihyperglycemic, antihyperlipidemic and pancreatic beta cells regeneration potentials of Onosma hispidum (ratanjot) root extracts in alloxan-induced diabetic rabbits.

Accepted: 
13 Feb, 2017
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Journal Authors: 
e-Published: 02 Mar, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

The Effects on Offsprings of Diabetes Mellitus Induced by Different Chemical Agents in Pregnant Rats with Advanced Pregnancy

DOI: 
10.7727/wimj.2015.587
Synopsis: 
Diabetes is the most important cause of perinatal mortality, and a four to eight-fold greater malformation rate is observed among babies of diabetic mothers than among the general population. Cardiac anomalies and central nervous system anomalies are the most common anomalies observed in babies of diabetic mothers.

ABSTRACT

Accepted: 
07 Dec, 2015
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 30 Mar, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

A Study of the Association between Diabetes Mellitus and Chronic Hepatitis B Virus Infection

Issue: 
DOI: 
10.7727/wimj.2015.236
Pages: 
108–14
Synopsis: 
The present study was designed to evaluate the relationship between HBV infection and type 2 diabetes mellitus first time from Pakistan and found that HBV infection did not enhance the risk of diabetes despite the significant differences in the biochemical parameters among the study's sample.

ABSTRACT

Background: Hepatitis B virus (HBV) infection and diabetes mellitus are major health problems associated with significant morbidity and mortality. The published literature suggests an association of diabetes mellitus with liver disease. However, the role of HBV infection in diabetes aetiology is still controversial. The present study was conducted to explore the veracity of this enigmatic association among Pakistani subjects.

Accepted: 
25 Nov, 2015
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Journal Sections: 
e-Published: 30 Mar, 2016

Comparative Evaluation of Dyslipaedemia in Obese and Diabetic Patients in Rural and Urban Areas in Lahore, Pakistan

DOI: 
10.7727/wimj.2015.327
Synopsis: 
The present study indicated that combined obesity and diabetes were the major cause of dyslipaedemia and coronary artery disease (CAD) followed by obesity and diabetes. Moreover, the risk of dyslipaedemia and CAD in the urban population, was not significantly different from the rural population.

ABSTRACT

Objective: Obesity and diabetes mellitus are interconnected conditions that share a number of pathophysiological mechanisms such as dyslipidemia leading to cardiovascular complications. The present study was conducted to determine the individual and combined effect of diabetes mellitus and obesity on dyslipidemia and ultimately on silent coronary artery disease (CAD).

Accepted: 
25 Aug, 2015
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Journal Sections: 
e-Published: 16 Mar, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Evaluative Research on Pharmacist-managed Diabetes Care: Focus on Self-monitoring of Blood Glucose

Issue: 
DOI: 
10.7727/wimj.2015.529
Pages: 
101–107
Synopsis: 
This pharmacist evaluative research study (PHARMERS) sought to empower pharmacists to assist in the management of poorly-controlled, diabetic patients. We hoped to demonstrate that patients stand a better chance of achieving improved glycaemic control if closely monitored by a pharmacist.

Abstract

Objective: Pharmacists have not demonstrated the ability to manage chronic diseases such as Type 2 Diabetes Mellitus, which is an ongoing problem in Trinidad and Tobago. The primary objective was to demonstrate that pharmacists can assist patients to achieve at least a 1% decrease in glycosylated haemoglobin (HbA1c ).

Accepted: 
17 Nov, 2015
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Journal Authors: 
e-Published: 15 Mar, 2016

Extra-pulmonary Tuberculosis, Multi Drug Resistant-Tuberculosis and Diabetes Mellitus: Two Case Series highlighting the need for Clinical Screening for Tuberculosis in Diabetes Mellitus Patients

DOI: 
10.7727/wimj.2015.212
Synopsis: 
There is an increased burden of diabetes mellitus (DM) in resource poor setting, coupled with the susceptibility to co-infection with tuberculosis (TB) especially in a high endemic tuberculosis area. Programmatic re-engineering of screening for TB amongst DM patients is needed to ensure a control of an ongoing silent co-epidemic of DM and TB. These case studies highlight the risk of the acquisition of TB among DM patients in line with the current clinical guidelines. The case series showed the importance of incorporating TB screening among DM patients into clinical practice needs to be intensified in order to improve the outcomes of both tuberculosis and control the epidemics.

ABSTRACT

Accepted: 
27 Apr, 2015
Journal Sections: 
e-Published: 26 Jun, 2015

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Study of Sex Hormone-binding Globulin Gene Polymorphism and Risk of Type 2 Diabetes Mellitus in Egyptian Men

Issue: 
DOI: 
10.7727/wimj.2014.088
Pages: 
338–43
Synopsis: 
Sex hormone-binding globulin gene polymorphisms are associated with higher risk of Type 2 diabetes mellitus in Egyptian men, through lowering circulating levels of sex hormone-binding globulin and consequently lowering testosterone and elevating oestradiol levels, which may be linked to insulin resistance.

ABSTRACT

Accepted: 
23 Apr, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 15 May, 2015

Prevalence of Chronic Kidney Disease among Patients Attending a Specialist Diabetes Clinic in Jamaica

Issue: 
DOI: 
10.7727/wimj.2014.084
Pages: 
201–8
Synopsis: 
This study estimated the prevalence of chronic kidney disease (CKD) among patients of the University Hospital of the West Indies diabetes clinic in Jamaica and evaluated the proportion of patients at high risk for adverse outcomes. Approximately 86% of patients had CKD and 70% were at high risk for adverse outcomes.

ABSTRACT

Objective: To estimate the prevalence of chronic kidney disease (CKD) among patients attending the University Hospital of the West Indies (UHWI) Diabetes Clinic and to determine the proportion of patients at high risk for adverse outcomes.

Accepted: 
23 Apr, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 04 May, 2015

Antidiabetic Evaluation of Momordica charantia L Fruit Extracts

Issue: 
DOI: 
10.7727/wimj.2013.180
Pages: 
294–9
Synopsis: 
Antidiabetic activities (hypoglycaemic, hypolipidaemic and pancreatic beta cells regeneration) of Momordica charantia (MC) fruits were investigated in alloxan diabetic rabbits. Although MC extracts showed significant hypoglycaemic effects (p < 0.05), these did not result in normal glucose and lipid profile levels. Regeneration of pancreatic beta cells by MC extracts was minimal, with fractional improvement produced by glibenclamide.

ABSTRACT

Accepted: 
29 Oct, 2013
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 08 May, 2014

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