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Compliance with Intramuscular Penicillin Prophylaxis in Children with Sickle Cell Disease in Jamaica

Intramuscular penicillin prophylaxis, despite commonly perceived challenges, is a practical option which can contribute to better patient compliance and thus significantly impact global rates of invasive pneumococcal disease and its complications in children with SCD and other similar conditions.


Objective: Penicillin prophylaxis is important in the defence against invasive pneumococcal disease in sickle cell disease (SCD). Penicillin may be administered by the oral route or by the intramuscular (IM) route. Compliance with the oral route, although difficult to assess, has been reported to be highly variable and often poor. We sought to determine the compliance rate with intramuscular penicillin (IM) prophylaxis in children with sickle cell disease.

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e-Published: 17 Oct, 2013
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