This cross-sectional study explored and generated novel and useable estimates of association between variants within genes underlying the transmethylation and trans-sulphuration pathways and inter-individual phenotypic variation in sickle cell anaemia (HbSS).
This study investigated the association of radiological abnormalities and asymptomatic bacteriuria in patients with sickle cell disease. No association was seen and there was no increased risk of symptomatic urinary tract infections in these patients.
Objective: The prevalence of asymptomatic bacteriuria (ASB) in sickle cell disease (SCD) in Jamaica is 5.3%. This study sought to determine the association between ASB and anatomical urological abnormalities and symptomatic urinary tract infections (UTIs).
This report represents a retrospective case series of males with sickle cell disease who have recurrent episodes of ischaemic priapism and were being treated with hydroxyurea for other indications. We evaluated the changes in priapism episodes in these patients.
This paper reports on obstetric outcomes of subjects, diagnosed with subclinical hypothyroidism, who were treated with l-thyroxine, and seeks to determine if these outcomes were equivalent to those of euthyroid subjects.
Objective: Restoration of euthyroidism with l-thyroxine reportedly reduces obstetric complications associated with subclinical hypothyroidism (SCH). The objective was to determine if obstetric outcomes of treated subjects were equivalent to euthyroid subjects.
Fifty-two placentae of Jamaican mothers, with a mean age of 29 years, at term were collected. Samples were analysed using Instrumental Neutron Activation Analysis for mercury and 9 other elements. Data were correlated with several parameters collected at delivery and by questionnaire data.
Aim: To investigate the relationships, if any, between elemental content of the placenta with age of mother, birthweight and the Apgar scores of a neonate.