ABSTRACT

Objective: Penicillin prophylaxis is important in the defence against invasive pneumococcal disease in sickle cell disease (SCD). Penicillin may be administered by the oral route or by the intramuscular (IM) route. Compliance with the oral route, although difficult to assess, has been reported to be highly variable and often poor. We sought to determine the compliance rate with intramuscular penicillin (IM) prophylaxis in children with sickle cell disease.

ABSTRACT

Objective: A series of tetraketones has been synthesized by way of a one pot synthesis and screened for inhibitory activity against the enzyme lipoxygenase.

ABSTRACT

Objective: To describe the drug prescribing pattern for hypertension at primary healthcare facilities throughout Trinidad.

Methods: A descriptive, cross-sectional survey was conducted at 22 primary healthcare facilities across Trinidad using a de novo, pilot-tested questionnaire during June to August 2006.