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S Ali

Compliance with Intramuscular Penicillin Prophylaxis in Children with Sickle Cell Disease in Jamaica

Issue: 
Pages: 
177–80
Synopsis: 
Intramuscular penicillin prophylaxis, despite commonly perceived challenges, is a practical option which can contribute to better patient compliance and thus significantly impact global rates of invasive pneumococcal disease and its complications in children with SCD and other similar conditions.

ABSTRACT


Objective: Penicillin prophylaxis is important in the defence against invasive pneumococcal disease in sickle cell disease (SCD). Penicillin may be administered by the oral route or by the intramuscular (IM) route. Compliance with the oral route, although difficult to assess, has been reported to be highly variable and often poor. We sought to determine the compliance rate with intramuscular penicillin (IM) prophylaxis in children with sickle cell disease.

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Journal Sections: 
e-Published: 17 Oct, 2013

Lipoxygenase Inhibitory Tetraketones: Potential Remedial Source for Inflammation and Asthma

Issue: 
Pages: 
92–8
Synopsis: 
Twenty-one tetraketones were synthesized in high yields by condensation of cyclohexane-1, 3-dione with a variety of aldehydes in the presence of tetraethyl ammonium bromide (Et4N+Br¯) as catalyst under mild reaction conditions. Most of these compounds showed significant inhibitory activity against the enzyme lipoxygenase.

ABSTRACT

Objective: A series of tetraketones has been synthesized by way of a one pot synthesis and screened for inhibitory activity against the enzyme lipoxygenase.

PDF Attachment: 
Journal Sections: 
e-Published: 17 Sep, 2013

Drug Prescribing for Hypertension at Primary Healthcare Facilities in Trinidad

Issue: 
Pages: 
43–8
Synopsis: 
A cross-sectional survey at primary healthcare centres in Trinidad among hypertensive patients showed an attempt to follow prescribing guidelines. Angiotensin converting enzyme inhibitors were most commonly prescribed, but thiazide diuretics were underutilized.


ABSTRACT

Objective: To describe the drug prescribing pattern for hypertension at primary healthcare facilities throughout Trinidad.

Methods: A descriptive, cross-sectional survey was conducted at 22 primary healthcare facilities across Trinidad using a de novo, pilot-tested questionnaire during June to August 2006.

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Journal Sections: 
e-Published: 19 Aug, 2013
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