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J Knight-Madden

Newborn Screening for Sickle Cell Disease in Jamaica: A Review – Past, Present and Future

Issue: 
DOI: 
10.7727/wimj.2013.107
Pages: 
147–50
Synopsis: 
Screening newborns for sickle cell disease (SCD) in Jamaica has significantly impacted mortality and morbidity of affected children. Efforts must continue toward the goal of island-wide newborn screening for SCD in order to ensure continued improvements.
 
ABSTRACT
 
Accepted: 
22 Apr, 2013
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e-Published: 11 Apr, 2014

Compliance with Intramuscular Penicillin Prophylaxis in Children with Sickle Cell Disease in Jamaica

Issue: 
Pages: 
177–80
Synopsis: 
Intramuscular penicillin prophylaxis, despite commonly perceived challenges, is a practical option which can contribute to better patient compliance and thus significantly impact global rates of invasive pneumococcal disease and its complications in children with SCD and other similar conditions.

ABSTRACT


Objective: Penicillin prophylaxis is important in the defence against invasive pneumococcal disease in sickle cell disease (SCD). Penicillin may be administered by the oral route or by the intramuscular (IM) route. Compliance with the oral route, although difficult to assess, has been reported to be highly variable and often poor. We sought to determine the compliance rate with intramuscular penicillin (IM) prophylaxis in children with sickle cell disease.

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e-Published: 17 Oct, 2013

The Prevalence of Marijuana Smoking in Young Adults with Sickle Cell Disease: A Longitudinal Study

Issue: 
Pages: 
224–7
Synopsis: 
A history of marijuana smoking was common in young adults with sickle cell disease. Usage increased between 2000 and 2004, and was seldom for medicinal purposes.

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e-Published: 10 Jun, 2013

Skin Test Reactivity to Aeroallergens in Jamaicans: Relationship to Asthma

Issue: 
Pages: 
142–7
Synopsis: 
Although skin prick test reactivity to house dust mite is more common in Jamaican adults and children, it is reactivity to cockroach which is significantly associated with asthma in adults.

ABSTRACT

Background: Asthma causes significant morbidity and mortality in the developing world. It is thus important to identify modifiable risk factors.

Objectives: To undertake a cross-sectional study to determine the prevalence of skin test reactivity to aeroallergens in Jamaican children and adults and the relationship of the diagnosis of asthma to the pattern of skin test positivity.

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e-Published: 10 Jun, 2013
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