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multidrug-resistance

16S rRNA Methyltransferases in Clinical Gram-negative Bacilli from a Tertiary Care Hospital in the Caribbean

DOI: 
10.7727/wimj.2018.131
Pages: 
Synopsis: 
16S rRNA methyltransferase enzymes pose an iminent threat to the availability of aminoglycosides as an emipiric therapeutic option for Gram negative bacterial infections. Their presence in the Caribbean therfore further burdens this resource limited region.

ABSTRACT

 

Objective: 16S rRNA methyltransferase enzymes or RMT confer pan-resistance to the aminoglycoside class of antibiotics. Multidrug-resistant Gram-negative bacilli with these methyltransferase genes have been identified from clinical settings in Europe, Asia and the Americas. This study reports their detection and characterization in Jamaican Multidrug-resistant Gram-negative bacilli.

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e-Published: 08 Mar, 2019

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