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PCR- RFLP

Performance Assessment of the Polymerase Chain Reaction-Restriction Fragment Length Polymorphism Method for Rapid Detection of Susceptibility to Ethambutol and Molecular Prediction of XDR Tuberculosis in Clinical Isolates of Mycobacterium tuberculosis

Issue: 
DOI: 
10.7727/wimj.2014.022
Pages: 
325–32
Synopsis: 
Fast detection of susceptibility to ethambutol drug is possible by polymerase chain reaction-restriction fragment length polymorphism. The embB306 locus is a candidate marker for rapid prediction of high resistance to anti-tuberculosis drugs for multidrug and extensively drug resistant forms of tuberculosis.

 ABSTRACT

Introduction: The polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method was employed for rapid detection of ethambutol (EMB) resistant clinical isolates of Mycobacterium tuberculosis.

Accepted: 
19 Jun, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 12 Jun, 2015
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